Prevalence of Increased Risk of Study Conditions According to Reference Standard Risk Assessment
| Measure | Type 2 Diabetes | Heart Disease | Breast Cancer | Ovarian Cancer | Colorectal Cancer | Prostate Cancer | Melanoma |
|---|---|---|---|---|---|---|---|
| Number excluded because of personal history of condition | 3 | 6 | 6 | 1 | 0 | 0 | 7 |
| Number excluded because of ineligible sex | n/a | n/a | 120 | 120 | n/a | 400 | n/a |
| Sample size for analysis of increased risk, No. | 520 | 523 | 400 | 405 | 526 | 120 | 519 |
| Prevalence of increased risk according to 3-generation pedigree analysis,a No. (%) | 120 (23.1) | 87 (16.6) | 37 (9.3) | 28 (6.9) | 34 (6.5) | 6 (5.0) | 54 (10.4) |
n/a = not applicable.
↵a Prevalence of increased risk of at least 1 condition was 51.5% (263 of 511) after excluding patients with a personal history of any condition.