Table 2

Indices of the Diagnostic Accuracy of Classification of Patients as Having vs Not Having Uncontrolled Blood Pressure Based on the Number of SBP Elevations

Definition of Uncontrolled Blood Pressure and Index	Unadjusted		Adjusted^a

	Cut Point	Value	Cut Point	Value
24-hour ABP SBP ≥130 mm Hg
AUC^b	≥3 elevations	0.712	≥3 elevations	0.722
NRI^c	≥3 elevations	0.005	≥3 elevations	0.004
Category-free NRI^c	≥3 elevations	0.010	≥2 elevations	0.192
rIDI^d	≥3 elevations	1.021	≥3 elevations	1.018
Deviance^e	≥3 elevations	321.9	≥3 elevations	321.1
24-hour ABP daytime SBP
≥135 mm Hg
AUC^b	≥2 elevations	0.717	≥2 elevations	0.724
NRI^c	≥2 elevations	0.072	≥2 elevations	0.072
Category-free NRI^c	≥2 elevations	0.144	≥2 elevations	0.137
rIDI^d	≥2 elevations	1.306	≥2 elevations	1.237
Deviance^e	≥2 elevations	331.9	≥2 elevations	330.3

ABP = ambulatory blood pressure; AUC = area under the receiver operating characteristic curve; NRI = net reclassification index; rIDI = relative integrated discrimination improvement; SBP = systolic blood pressure.
↵a For age, sex, and body mass index.
↵b Criterion: largest value for receiver operating characteristic curve produced from all 10 cut points (≥1 elevations, ≥2 elevations, ≥3 elevations, …, ≥9 elevations, 10 elevations).
↵c Criterion: last classification before that producing first negative value.
↵d Criterion: last classification before that producing first value below unity.
↵e Model deviance, criterion: last classification before that producing first higher value.
Note: Elevated systolic blood pressure was defined as 24-hour ABP SBP ≥130 mm Hg or 24-hour ABP daytime SBP ≥135 mm Hg. Number of elevations was defined as number of elevations ≥135 mm Hg among the last 10 recordings of morning and evening home SBP.