Table 1

Baseline Characteristics of the Study Cohort (N = 598)

CharacteristicFinal Diagnosis P Value
PE (n = 73)Other (n = 525)
Age, mean (SD), y53 (15.0)47 (16.0).004
Male, No. (%)25 (34.2)148 (28.2).29
Clinical signs and symptoms of DVT, No. (%)26 (35.6)31 (5.9)<.001
Alternative diagnosis less likely, No. (%)61 (83.6)272 (51.8)<.001
Heart rate >100/min, No. (%)25 (34.2)86 (16.4)<.001
Immobilization, No. (%)23 (31.5)71 (13.5)<.001
Previous PE or DVT, No. (%)18 (24.7)66 (12.6).005
Hemoptysis, No. (%)5 (6.8)16 (3.0).19
Malignancy, No. (%)5 (6.8)21 (4.0).42
Gestalt probability,a median % (IQR)70 (40.0)30 (32.0)<.001
Wells rule score,b median (IQR)4.5 (4.0)3.0 (3.5)<.001
Positive d-dimer test,c No. (%)61 (83.6)198 (37.7)<.001

  • DVT = deep venous thrombosis; IQR = interquartile range; PE = pulmonary embolism.

  • ↵a Estimated PE probability by family physician.

  • ↵b Possible values range from 0 to 12.5, with higher values indicating a greater probability of PE.

  • ↵c Clearview Simplify point-of-care assay.