Table 1

Patient Characteristics at Baseline

CharacteristicPlacebo-First Arm (n = 17)Nifedipine-First Arm (n = 15)
Age, mean, y5059
 Women, No.810
 Men, No.95
Chilblain symptoms
 Mean duration at intake, wk76
 Experiencing first episode, No.22
 Experienced >1 episode, No.44
 Experiences episode every year, No.1210
Mean VOC score, mma,b2524
Mean VOD score, mmb1715
Smoking, No.33
 Diabetes, No.01
 Peripheral arterial disease, No.10
 Raynaud phenomenon, No.63
Relevant medication use
 β-blocker, No.00
 Nicotine replacement drug, No.00
 Acetylsalicylic acid, No.01
 ACE or angiotensin II receptor blocker, No.32
  • ACE = angiotensin-converting enzyme; VOC = visual analogue scale on complaints; VOD = visual analogue scale on disability.

  • a The higher of either the visual analogue scale itch score or the visual analogue scale pain score.

  • b Scores measured on 100-mm scales where higher values indicate more complaints (symptoms) or greater disability.