Characteristics of Studies Reporting the Prevalence of Group C beta hemolytic Streptococcus and Fusobacterium necrophorum
| Author, Year (Country) | Population | Age | Settinga | Years of Data Collection | Diagnostic Method |
|---|---|---|---|---|---|
| Group C Streptococci | |||||
| Lindbaek et al,4 2005 (Norway) | Adults and children with sore throat for <7 d and no recent antibiotic presenting to GP. | Mean 23.9 y; 244 adults, 62 children <10 y | Primary care | 2000–2002 | Culture |
| Fretzayas et al,17 2009 (Greece) | Children with pharyngitis and no recent antibiotics presenting to an outpatient clinic. | Mean 6.5 y, range 4 y–14 y | Primary care | 2006 | Culture |
| Little et al,5 2012 (England) | Adults and children presenting to a GP with sore throat for <14 d as the primary symptom. | ≥5 y; 11% were 5 y–9 y | Primary care | 2007–2008 | Culture |
| Cohen et al,18 2012 (France) | Children with pharyngitis and no recent antibiotics presenting to their pediatrician. | Mean 6.1 y, range 3 y–5 y | Primary care | 2008–2010 | Culture |
| Llor et al,19 2009 (Spain) | Adults presenting to GP with acute pharyngitis and ≥2 Centor criteria. | Mean 30.6 y, range ≥14 yr | Primary care | 2007–2008 | Culture |
| Calvino et al,20 2014 (Spain) | Adults presenting to an outpatient health center with pharyngitis and all 4 Centor criteria. | Mean 28.5 y, range 18 y–51 y | Primary care | 2010–2012 | Culture |
| Fusobacterium necrophorum | |||||
| Ludlam et al,21 2009 (United Kingdom) | Two groups: 411 students, of whom 85 had a sore throat, and 103 patients presenting to a GP with sore throat. | University students: median 20 y, range 18 y–39 y GP patients: median 26 y, range 2 y–77 y | Primary care | 2005–2006 | PCR |
| Bank et al,16 2010 (Denmark) | All throat swabs submitted to a regional laboratory from primary care practice during 2 mo. | Median 20 y, range 0 y–57 y | Laboratory-based | 2009 | PCR |
| Bank et al,22 2013 (Denmark) | All throat swabs submitted to a regional laboratory from primary care practices for patients age 15 y–24 y. | Range 15 y-24 y | Laboratory-based | 2007–2009 | Culture |
| Both pathogens | |||||
| Aliyu et al,23 2004 (United Kingdom) | Random sample of 100 throat swabs submitted by primary care physicians during 7 mo. | Mean 25 y, range 5 mo-79 y | Laboratory-based | 2003 | Culture |
| Batty et al,24 2005 (United Kingdom) | All throat swabs received during a 4 wk period. | 1 y–47 y | Laboratory-based | 2005 | Culture |
| Amess et al,10 2007 (United Kingdom) | All throat swabs received during 6 mo. | <1 y to 88 y | Laboratory-based | 2004–2005 | Culture |
| Jensen et al,25 2007 (Denmark) | All throat swabs received during 7 mo from patients with a diagnosis consistent with tonsillitis or pharyngitis. | Range 18 y–32 y | Laboratory-based | 2005–2006 | PCR |
| Eaton et al,26 2014 (United Kingdom) | All throat swabs received during 1 y. | Not reported; largely 10 y–49 y | Laboratory-based | 2011–2012 | Culture |
| Hedin et al,27 2015 (Sweden) | Adults presenting to a GP with acute pharyngo-tonsillitis. | Median 33 y, range 15 y–48 y | Primary care | 2011–2012 | Culture |
| Centor et al,7 2015 (United States) | Adults with sore throat presenting to a college health center. | Mean 22.3 y, range 15 y–30 y | Primary care | 2013–2014 | PCR |
GP = general practitioner; PCR = polymerase chain reaction.
↵a Primary care includes outpatient generalist clinics such as general practice, family medicine, general internal medicine, and pediatrics.