Table 3

Predicted Lifetime Health and Cost Outcomes of CVD Clinical Preventive Services in US Population Groups

Preventive ServiceUS AdultsMenWomen
Non-Hispanic WhiteNon-Hispanic BlackHispanicNon-Hispanic WhiteNon-Hispanic BlackHispanic
Aspirin for primary prevention
Health impact, QALY2,2002,7006,8002,3003005,000100
Cost-effectiveness, $31 saved pp50 saved pp166 saved pp47 saved pp16,700/QALY14 saved pp60,200/QALY
CVD events, No.−530−750−2,030−840−20−530−20
 MI events−300−470−930−530−20−190−10
 Stroke events−100−110−420−110Longevitya−240−10
 CVD deaths−80−110−340−150−10−100−10
CRC cases, No.−280−370−860−390−80−370−20
Persons treated for primary prevention, No.15,60022,00039,20027,5002,30021,0002,200
Total costs, $ million−3.1−5.0−16.6−4.70.8−1.41.1
 Disease costs−5.5−7.9−21.7−8.3−0.3−4.8−0.2
 Screening costs1.11.11.11.30.81.11.1
 Treatment costs1.41.84.02.30.22.30.2
Cholesterol screening
Health impact, QALY14,30017,50025,60019,7007,90014,2009,100
Cost-effectiveness, $/QALY33,80029,40022,90025,60056,50042,10048,900
CVD events, No.−3,960−5,090−6,630−5,320−2,150−3,520−2,940
 MI events−1,500−2,150−2,860−2,070−700−960−930
 Stroke events−40−150Longevitya−40Longevitya−130−20
 CVD deaths−1,010−1,120−1,450−1,220−820−1,120−630
Persons treated for primary prevention, No.40,10043,30051,40045,50032,50043,10036,000
Total costs, $ million80.189.0106.490.161.390.965.1
 Disease costs−36.3−51.5−76.4−58.8−12.1−22.6−21.9
 Screening costs16.117.718.618.513.118.214.4
 Treatment and management costs100.3122.8164.3130.360.295.472.5
Hypertension screening
Health impact, QALY15,60011,80017,00014,90016,50024,70016,300
Cost-effectiveness, $/QALY48,50052,20060,60040,80048,30042,10049,500
CVD events, No.−4,000−3,460−3,740−4,060−3,920−5,930−4,610
 MI events−750−880−970−860−600−630−690
 Stroke events−1,020−680−860−720−1,100−2,250−1,180
 CVD deaths−1,010−780−1,080−1,040−1,070−1,480−1,080
Persons treated for primary prevention, No.53,40046,20058,90047,90056,70064,70059,000
Total costs, $ million122.9105.7184.6102.7119.7176.4121.6
 Disease costs−34.8−33.6−37.5−31.6−30.7−58.2−38.0
 Screening costs33.834.227.434.435.428.834.9
 Treatment and management costs124.0105.1194.799.9115.0205.9124.8
  • CRC = colorectal cancer; CVD = cardiovascular disease; MI = myocardial infarction; pp = per person; QALY = quality-adjusted life year.

  • Note: All outcomes are standardized for comparison purposes to reflect the lifetime of a 100,000 person US-representative birth cohort within each respective group starting at age 18 years. Cost-effectiveness is expressed in terms of incremental costs per QALY, unless a preventive service is cost-saving overall, in which case, it is expressed in terms of costs saved per person. All costs are expressed in 2012 US dollars.

  • a Population rates in the outcome are projected to stay the same or increase slightly due to increases in life expectancy attributable to the clinical preventive service.