Comparison of Clinical and Echocardiographic Characteristics Between Children With Pathologic and Physiologic Murmurs (N = 194)
| Characteristic | Pathologic Murmur (n=30) | Physiologic Murmur (n=164) | P Value |
|---|---|---|---|
| Age, y | 7.4 ± 3.8 | 6.2 ± 3.3 | .07 |
| Sex, % (No.) | |||
| Male | 57 (17) | 64 (105) | .53 |
| Female | 43 (13) | 36 (59) | |
| Symptoms, % (No.) | 1.00 | ||
| Yes | 20 (6) | 9 (14) | <.001 |
| No | 80 (24) | 91 (150) | |
| Murmur present in standing position, % (No.) | |||
| Yes | 93 (28) | 40 (66) | <.001 |
| No | 7 (2) | 60 (98) | |
| Murmur intensity decreased in standing position, % (No.) | |||
| Yes | 43 (12) | 80 (53) | <.001 |
| No | 57 (16) | 20 (13) | |
| Murmur timing, % (No.) | |||
| Systolic | 97 (29) | 100 (164) | .16 |
| Diastolic | 0 (0) | 0 (0) | |
| Continuous | 3 (1) | 0 (0) | |
| Murmur location, % (No.) | |||
| Right upper sternal border | 13 (4) | 6 (9) | .76 |
| Left upper sternal border | 7 (11) | 10 (16) | <.001 |
| Low to middle left sternal border | 33 (10) | 82 (126) | <.001 |
| Apex | 13 (4) | 2 (3) | <.01 |
| Under left clavicle | 4 (1) | 0 (0) | .16 |
| Murmur radiation, % (No.) | |||
| Yes | 33 (10) | 15 (25) | <.05 |
| No | 67 (20) | 85 (139) |