Table 1

Association Between Exposure to Oseltamivir or Influenza Alone and Suicide: Overall and Stratified by Individual Characteristics

Characteristic	Oseltamivir	Influenza Only
Analysis A: 10-day equivalent periods
Case, No.	253^a	173^a
Exposed	24	17
Unexposed	229	156
Control, No.	949	647
Exposed	124	89
Unexposed	825	558
Overall, OR (95% CI)	0.64 (0.39–1.00)^b	0.63 (0.34–1.08)
Sex, OR (95% CI)
Male	0.64 (0.31–1.32)	0.82 (0.36–1.86)
Female	0.64 (0.34–1.05)	0.52 (0.25–1.07)
Age-group, OR (95% CI)
1–11 y	0.50 (0.11–2.27)	0.40 (0.04–3.69)
12–18 y	0.66 (0.41–1.04)	0.65 (0.37–1.12)
Mental health history, OR (95% CI)
No	0.62 (0.35–1.08)	0.51 (0.26–1.00)
Yes	0.68 (0.33–1.42)	0.99 (0.39–2.45)
History of suicide attempt, OR (95% CI)
No	0.62 (0.39–0.99)	0.30 (0.04–2.38)
Yes	0.91 (0.18–4.53)	0.67 (0.39–1.18)
Influenza vaccine during season, OR (95% CI)
No	0.71 (0.45–1.13)	0.60 (0.33–1.07)
Yes	0.19 (0.03–1.46)	0.84 (0.22–3.19)
Analysis B: 5-day case period, 10-day washout, 5-day control period
Case, No.	253	173
Exposed	16	10
Unexposed	237	163
Control, No.	985	673
Exposed	74	74
Unexposed	911	599
Overall association, OR (95% CI)	0.82 (0.45–1.43)	0.48 (0.22–0.95)^c
Analysis C: 15-day equivalent periods
Case, No.	253	173
Exposed	28	24
Unexposed	225	149
Control, No.	886	595
Exposed	150	96
Unexposed	736	499
Overall association, OR (95% CI)	0.57 (0.36–0.86)^d	0.72 (0.43–1.15)

OR=odds ratio.
↵a Individuals were allowed to contribute multiple cases, as long as they occurred in different influenza seasons. The 253 oseltamivir cases were contributed by 251 individuals. The 173 influenza cases were contributed 162 individuals.
↵b P = .05.
↵c P <.05.
↵d P <.01.