Elsevier

The Lancet

Volume 325, Issue 8428, 9 March 1985, Pages 540-545
The Lancet

CONTROLLED TRIAL OF OLIGOANTIGENIC TREATMENT IN THE HYPERKINETIC SYNDROME

https://doi.org/10.1016/S0140-6736(85)91206-1Get rights and content

Abstract

76 selected overactive children were treated with an oligoantigenic diet. 62 improved, and a normal range of behaviour was achieved in 21 of these. Other symptoms, such as headaches, abdominal pain, and fits, also often improved. 28 of the children who improved completed a double-blind, crossover, placebo-controlled trial in which foods thought to provoke symptoms were reintroduced. Symptoms returned or were exacerbated much more often when patients were on active material than on placebo. 48 foods were incriminated. Artificial colorants and preservatives were the commonest provoking substances, but no child was sensitive to these alone.

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1

Present address: Haunersches Kinderspital, Munich, West Germany.

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