BACKGROUND: The 4-item Patient Health Questionnaire-4 (PHQ-4) is an ultra-brief self-report
questionnaire that consists of a 2-item depression scale (PHQ-2) and a 2-item anxiety …

Importance When analyzing results of randomized clinical trials, the treatment with the greatest
specific effect compared with its placebo control is considered to be the most effective one…

Background The use of placebo interventions outside clinical trials is ethically, professionally
and legally controversial. Little is known about the frequency and circumstances of placebo …

PURPOSE We performed a systematic review of the currently available evidence on whether
psychological treatments are effective for treating depressed primary care patients in …

Background: In 1998, the National Institutes of Health Consensus Statement on Acupuncture
concluded that promising results have emerged showing the efficacy of acupuncture in …

Background While several recent large randomized trials found clinically relevant effects of
acupuncture over no treatment or routine care, blinded trials comparing acupuncture to sham …

PURPOSE The purpose of this study was to investigate whether antidepressants are more
effective than placebo in the primary care setting, and whether there are differences between …

OBJECTIVE: The aim of this study was to explore if patients’ preferences to be involved in
decision making correlates with reasons for encounter, psychological or demographic …

OBJECTIVE: Fibromyalgia syndrome (FMS) patients and their doctors frequently complain
on interaction difficulties. We investigated the effects of a shared decision-making (SDM) …

Background Measurement of FE NO might substitute bronchial provocation for diagnosing
asthma. We aimed to investigate the diagnostic accuracy of FE NO measurement compared …