User profiles for Claire Jackson

Claire L Jackson

University of Southampton
Verified email at soton.ac.uk
Cited by 2147

Achieving research impact through co‐creation in community‐based health services: literature review and case study

T Greenhalgh, C Jackson, S Shaw… - The Milbank …, 2016 - Wiley Online Library
Policy Points: Co‐creation—collaborative knowledge generation by academics working
alongside other stakeholders—is an increasingly popular approach to aligning research and …

Atrial‐like cardiomyocytes from human pluripotent stem cells are a robust preclinical model for assessing atrial‐selective pharmacology

…, JW Ford, JT Milnes, S El‐Haou, C Jackson… - EMBO molecular …, 2015 - embopress.org
Drugs targeting atrial‐specific ion channels, K v 1.5 or K ir 3.1/3.4, are being developed as
new therapeutic strategies for atrial fibrillation. However, current preclinical studies carried out …

[HTML][HTML] A novel ACE2 isoform is expressed in human respiratory epithelia and is upregulated in response to interferons and RNA respiratory virus infection

C Blume, CL Jackson, CM Spalluto, J Legebeke… - Nature …, 2021 - nature.com
Angiotensin-converting enzyme 2 (ACE2) is the main entry point in airway epithelial cells for
SARS-CoV-2. ACE2 binding to the SARS-CoV-2 protein spike triggers viral fusion with the …

[HTML][HTML] Co-design and implementation research: challenges and solutions for ethics committees

F Goodyear-Smith, C Jackson, T Greenhalgh - BMC medical ethics, 2015 - Springer
Background Implementation science research, especially when using participatory and co-design
approaches, raises unique challenges for research ethics committees. Such …

Mutations in CCDC39 and CCDC40 are the Major Cause of Primary Ciliary Dyskinesia with Axonemal Disorganization and Absent Inner Dynein Arms

…, R Wilson, T Taylor‐Cox, A Dewar, C Jackson… - Human …, 2013 - Wiley Online Library
Primary ciliary dyskinesia (PCD) is a genetically heterogeneous disorder caused by cilia and
sperm dysmotility. About 12% of cases show perturbed 9+2 microtubule cilia structure and …

Functional modulation of Crohn's disease myofibroblasts by anti-tumor necrosis factor antibodies

A Di Sabatino, SLF Pender, CL Jackson, JD Prothero… - Gastroenterology, 2007 - Elsevier
Background & Aims: Infliximab induces immune cell apoptosis by outside-to-inside
signaling through transmembrane tumor necrosis factor-α (mTNF). However, in inflamed gut, …

Nitric oxide in primary ciliary dyskinesia

WT Walker, CL Jackson, PM Lackie… - European …, 2012 - Eur Respiratory Soc
Nitric oxide is continually synthesised in the respiratory epithelium and is upregulated in
response to infection or inflammation. Primary ciliary dyskinesia (PCD) is characterised by …

Systematic review of integrated models of health care delivered at the primary–secondary interface: how effective is it and what determines effectiveness?

…, M Donald, IA Scott, J Dart, CL Jackson - Australian Journal of …, 2015 - CSIRO Publishing
Integrated multidisciplinary care is difficult to achieve between specialist clinical services
and primary care practitioners, but should improve outcomes for patients with chronic and/or …

Systematic review of interventions to improve prescribing

R Ostini, D Hegney, C Jackson… - Annals of …, 2009 - journals.sagepub.com
Objective: To update 2 comprehensive reviews of systematic reviews on prescribing
interventions and identify the latest evidence about the effectiveness of the interventions. Data …

[HTML][HTML] Culture of primary ciliary dyskinesia epithelial cells at air-liquid interface can alter ciliary phenotype but remains a robust and informative diagnostic aid

RA Hirst, CL Jackson, JL Coles, G Williams, A Rutman… - PloS one, 2014 - journals.plos.org
Background The diagnosis of primary ciliary dyskinesia (PCD) requires the analysis of ciliary
function and ultrastructure. Diagnosis can be complicated by secondary effects on cilia …