Objective To systematically review studies quantifying the associations of long term (clinic),
mid-term (home), and short term (ambulatory) variability in blood pressure, independent of …

Objective To assess the associations between statins and adverse events in primary
prevention of cardiovascular disease and to examine how the associations vary by type and …

Background and Objectives Randomization, allocation concealment, and blind outcome
assessment have been shown to reduce bias in human studies. Authors from the Collaborative …

Background Trials show that weight loss interventions improve biomarkers of non-alcoholic
fatty liver disease (NAFLD), but it is unclear if a dose-response relationship exists. Objective …

Objective To examine the association between antihypertensive treatment and specific
adverse events. Design Systematic review and meta-analysis. Eligibility criteria Randomised …

Hypertension has been identified as a risk factor for coronavirus disease 2019 (COVID-19)
and associated adverse outcomes. This study examined the association between …

… This manuscript presents work carried out as part of a DPhil scholarship awarded to
Constantinos Koshiaris funded by the Primary Care Research Trust, the University of Oxford, and …

Background We aimed to understand the time period of cancer diagnosis and the cancer
types detected in primary care patients with unexpected weight loss (UWL) to inform cancer …

Background Antihypertensives are effective at reducing the risk of cardiovascular disease,
but limited data exist quantifying their association with serious adverse events, particularly in …

Background: International guidelines recommend that primary care clinicians recognize
obesity and offer treatment opportunistically, but there is little evidence on how clinicians can …