[HTML][HTML] Effect of parathyroid hormone (1-34) on fractures and bone mineral density in postmenopausal women with osteoporosis
…, HK Genant, O Wang, D Mellström… - New England journal …, 2001 - Mass Medical Soc
Background Once-daily injections of parathyroid hormone or its amino-terminal fragments
increase bone formation and bone mass without causing hypercalcemia, but their effects on …
increase bone formation and bone mass without causing hypercalcemia, but their effects on …
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture
…, P Lips, Ö Ljunggren, RS Lorenc, J Marc, D Mellström… - Nature …, 2012 - nature.com
Bone mineral density (BMD) is the most widely used predictor of fracture risk. We performed
the largest meta-analysis to date on lumbar spine and femoral neck BMD, including 17 …
the largest meta-analysis to date on lumbar spine and femoral neck BMD, including 17 …
A meta‐analysis of trabecular bone score in fracture risk prediction and its relationship to FRAX
…, Ö Ljunggren, M Lorentzon, D Mellström… - Journal of bone and …, 2016 - academic.oup.com
Trabecular bone score (TBS) is a gray‐level textural index of bone microarchitecture derived
from lumbar spine dual‐energy X‐ray absorptiometry (DXA) images. TBS is a bone mineral …
from lumbar spine dual‐energy X‐ray absorptiometry (DXA) images. TBS is a bone mineral …
Five years of denosumab exposure in women with postmenopausal osteoporosis: results from the first two years of the FREEDOM extension
…, MA Krieg, Z Man, D Mellström… - Journal of Bone and …, 2012 - academic.oup.com
The 3‐year FREEDOM trial assessed the efficacy and safety of 60 mg denosumab every 6
months for the treatment of postmenopausal women with osteoporosis. Participants who …
months for the treatment of postmenopausal women with osteoporosis. Participants who …
A meta‐analysis of the association of fracture risk and body mass index in women
…, E Lau, WD Leslie, D Mellström… - Journal of bone and …, 2014 - academic.oup.com
Several recent studies suggest that obesity may be a risk factor for fracture. The aim of this
study was to investigate the association between body mass index (BMI) and future fracture …
study was to investigate the association between body mass index (BMI) and future fracture …
Whole‐genome sequencing identifies EN1 as a determinant of bone density and fracture
…, N Garcia‐Giralt, LL Launer, V Gudnason, D Mellström… - Nature, 2015 - nature.com
The extent to which low‐frequency (minor allele frequency (MAF) between 1–5%) and rare (MAF
≤ 1%) variants contribute to complex traits and disease in the general population is …
≤ 1%) variants contribute to complex traits and disease in the general population is …
Plasma osteocalcin is inversely related to fat mass and plasma glucose in elderly Swedish men
…, Å Tivesten, U Smith, D Mellström - Journal of Bone and …, 2009 - academic.oup.com
The osteoblast‐derived protein osteocalcin has recently been shown to affect adiposity and
glucose homeostasis in mice, suggesting that the skeleton influences energy metabolism …
glucose homeostasis in mice, suggesting that the skeleton influences energy metabolism …
[HTML][HTML] Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study
…, H Melhus, E Ingelsson, D Mellström… - The lancet Diabetes & …, 2014 - thelancet.com
Background Low plasma 25-hydroxyvitamin D (25[OH]D) concentration is associated with
high arterial blood pressure and hypertension risk, but whether this association is causal is …
high arterial blood pressure and hypertension risk, but whether this association is causal is …
Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile
…, M Lorentzon, RN Luben, B McKnight, D Mellström… - Nature …, 2011 - nature.com
Genome-wide association studies have identified 32 loci influencing body mass index, but
this measure does not distinguish lean from fat mass. To identify adiposity loci, we meta-…
this measure does not distinguish lean from fat mass. To identify adiposity loci, we meta-…
The effect of three or six years of denosumab exposure in women with postmenopausal osteoporosis: results from the FREEDOM extension
…, E Czerwiński, MA Krieg, D Mellström… - The Journal of …, 2013 - academic.oup.com
Context: The Fracture Reduction Evaluation of Denosumab in Osteoporosis Every 6 Months
(FREEDOM) extension is evaluating the long-term efficacy and safety of denosumab for up …
(FREEDOM) extension is evaluating the long-term efficacy and safety of denosumab for up …