Consensus definitions have been reached for both acute kidney injury (AKI) and chronic
kidney disease (CKD) and these definitions are now routinely used in research and clinical …

The 5(R) and 5(S) hydroxyeicosatetraenoic acids (5[R]-HETE, 5[S]-HETE) are important
inflammatory mediators in lung diseases: they increase mucus, induce airway contraction, and …

Objective Linked metabolic and cardiovascular comorbidities are prevalent in
hyperuricemia and gout. For mechanistic insight into impact on inflammatory processes and …

A 16-year-old female basketball player presented with a 2½-year history of exercise-induced
severe dyspnea, stridor, and mild wheezing that did not respond to prophylactic treatment …

Cytokines are proinflammatory protein mediators produced by many cells, including mast
cells, T Iymphocytes, eosinophils, airway epithelial cells, and macrophages. There are …

Interleukin-1 alpha (IL-1 alpha) is a cytokine with a myriad of potent proinflammatory effects.
Neutrophils are important immune effector cells in allergic and inflammatory lung diseases. …

A case is reported in a 67-yr-old woman from Iowa, USA, with culture-positive Coccidioides
immitis tenosynovitis of the left wrist, who developed small, discrete, pruritic erythematous …

Eosinophilic fasciitis 2 is a rare syndrome consisting5 of:(1) localised skin involvement;(2)
pronounced thickening of the subcutaneous fascia;(3) absence of visceral changes and …

The Rothman Index (RI) gives a visual picture of patient9s condition and progress for the
physician and family to view together. This case demonstrates how the RI graph facilitates …

A few years into my practice at the Veterans Affairs (VA) clinic, I was threatened by an angry
patient when I had to discontinue his opioids. I placed a civil restraining order against him …