Influenza viruses are causative agents of an acute febrile respiratory disease called influenza
(commonly known as “flu”) and belong to the Orthomyxoviridae family. These viruses …

Influenza virus assembly and morphogenesis require transport of viral components to the
assembly site at the apical plasma membrane of polarized epithelial cells and interaction …

In the past two decades, humans have faced many new viral infectious agents in emerging
and re-emerging infectious diseases (EIDs). Many factors contribute to the appearance of …

Monoclonal antibodies (MAbs) are potential new therapeutics for brain diseases. However,
MAbs do not cross the blood−brain barrier (BBB). The present work describes the genetic …

OBJECTIVE Nationwide studies on secular trends of diabetes complications are not available
in Asia. We examined changes in risk factor control and incidence of complications from …

Background— Evidence suggests that apolipoprotein AI (apoA-I) and HDL play important
roles in modulating inflammation. We previously reported that an apoA-I mimetic peptide, D-4F…

Decoy receptors, such as the human tumor necrosis factor receptor (TNFR), are potential new
therapies for brain disorders. However, decoy receptors are large molecule drugs that are …

Erythropoietin (EPO) is a neurotrophic factor that could be developed as a new drug for brain
disorders. However, EPO does not cross the blood-brain barrier (BBB). In the present study…

Adherence with oral hypoglycaemic agent is crucial to achieve optimal glycaemic control. The
8‐item Morisky Medication Adherence Scale (MMAS‐8) has been frequently used, yet the …

Mutations in the lysosomal enzyme, N-sulfoglucosamine sulfohydrolase (SGSH), also called
sulfamidase, cause accumulation of lysosomal inclusion bodies in the brain of children born …