Clock mechanisms in zebrafish

GM Cahill - Cell and tissue research, 2002 - Springer
Recent research on the circadian system of the zebrafish is reviewed. This teleost has
become an attractive model system because of its advantages for genetic analyses. Circadian …

Circadian clock functions localized in Xenopus retinal photoreceptors

GM Cahill, JC Besharse - Neuron, 1993 - cell.com
A circadian oscillator that regulates visual function is located somewhere within the vertebrate
eye. To determine whether circadian rhythmicity is generated by retinal photoreceptors, …

Circadian regulation of melatonin production in cultured zebrafish pineal and retina

GM Cahill - Brain research, 1996 - Elsevier
Melatonin release was measured from zebrafish pineal organs and retinas maintained in
flow-through culture. Pineal organs released melatonin in a strong circadian rhythm through 5 …

Circadian rhythms of locomotor activity in zebrafish

MW Hurd, J Debruyne, M Straume, GM Cahill - Physiology & behavior, 1998 - Elsevier
As part of an effort to characterize the circadian system of the zebrafish, we examined the
circadian regulation of locomotor activity in adult males and females. Gross locomotor activity …

Resetting the circadian clock in cultured Xenopus eyecups: regulation of retinal melatonin rhythms by light and D2 dopamine receptors

GM Cahill, JC Besharse - Journal of Neuroscience, 1991 - Soc Neuroscience
A circadian oscillator is located within the eye of Xenopus laevis. This oscillator regulates
retinal melatonin synthesis, stimulating it at night. The primary goal of the studies reported here …

Melatonin suppresses nighttime memory formation in zebrafish

O Rawashdeh, NH de Borsetti, G Roman, GM Cahill - Science, 2007 - science.org
Memory processes are modulated by the biological clock, although the mechanisms are
unknown. Here, we report that in the diurnal zebrafish both learning and memory formation of …

Circadian rhythmicity in vertebrate retinas: regulation by a photoreceptor oscillator

GM Cahill, JC Besharse - Progress in retinal and eye research, 1995 - Elsevier
Circadian regulation of retinal function has now been shown in all classes of vertebrates and
attempts are now under way to understand the mechanisms underlying this regulation. The …

Development of a circadian melatonin rhythm in embryonic zebrafish

N Kazimi, GM Cahill - Developmental Brain Research, 1999 - Elsevier
We investigated the time course of circadian system development in zebrafish and the role
of environmental light cycles in this process, using a rhythm in melatonin content of embryos …

Circadian rhythmicity in the locomotor activity of larval zebrafish

GM Cahill, MW Hurd, MM Batchelor - Neuroreport, 1998 - journals.lww.com
THE zebrafish (Danio rerio) may be useful for mutational analyses of vertebrate circadian clock
mechanisms if efficient assays of circadian rhythmicity are available. Using an automated …

Rhythmic regulation of retinal melatonin: metabolic pathways, neurochemical mechanisms, and the ocular circadian clock

GM Cahill, MS Grace, JC Besharse - Cellular and molecular neurobiology, 1991 - Springer
Current knowledge of the mechanisms of circadian and photic regulation of retinal melatonin
in vertebrates is reviewed, with a focus on recent progress and unanswered questions. 2. …