OBJECTIVE: The nine-item mood module of the Patient Health Questionnaire (PHQ-9) was
developed to screen and to diagnose patients in primary care with depressive disorders. We …

Background: Clinical probability assessment is combined with d-dimer testing to exclude
pulmonary embolism (PE). Purpose: To compare the test characteristics of gestalt (a physician's …

Controversy remains about the value of combined treatment with levothyroxine (LT 4 ) and
liothyronine (LT 3 ), compared with LT 4 alone in primary hypothyroidism. We compared …

PURPOSE Because recognition and management of patients with somatoform disorders
are difficult, we wanted to determine the specificity, sensitivity, and the test-retest reliability of …

BackgroundItem 9 of the Patient Health Questionnaire-9 (PHQ-9) queries about thoughts of
death and self-harm, but not suicidality. Although it is sometimes used to assess suicide risk, …

PURPOSE We wanted to summarize evidence about the diagnostic accuracy of the 5.07/10-g
monofilament test in peripheral neuropathy. METHODS We conducted a systematic review …

PURPOSE Although dizzy patients are predominantly seen in primary care, most diagnostic
studies on dizziness have been performed among patients in secondary or tertiary care. Our …

Objective To validate the use of the Wells clinical decision rule combined with a point of care
D-dimer test to safely exclude pulmonary embolism in primary care. Design Prospective …

Objective Despite the growing number of point-of-care (POC) tests available, little research
has assessed primary care clinician need for such tests. We therefore aimed to determine …

Background General Practitioners spend a disproportionate amount of time on frequent
attenders. So far, trials on the effect of interventions on frequent attenders have shown negative …