User profiles for James Gern

James Gern

Professor of Pediatrics and Medicine, University of Wisconsin-Madison
Verified email at medicine.wisc.edu
Cited by 42793

[HTML][HTML] Randomized trial of omalizumab (anti-IgE) for asthma in inner-city children

…, PJ Gergen, HE Mitchell, JE Gern… - … England Journal of …, 2011 - Mass Medical Soc
Background Research has underscored the effects of exposure and sensitization to allergens
on the severity of asthma in inner-city children. It has also revealed the limitations of …

Wheezing rhinovirus illnesses in early life predict asthma development in high-risk children

…, LP Salazar, DF DaSilva, CJ Tisler, JE Gern… - American journal of …, 2008 - atsjournals.org
Rationale: Virus-induced wheezing episodes in infancy often precede the development of
asthma. Whether infections with specific viral pathogens confer differential future asthma risk …

Role of viral respiratory infections in asthma and asthma exacerbations

WW Busse, RF Lemanske, JE Gern - The Lancet, 2010 - thelancet.com
Viral respiratory tract infections are common and usually selflimited illnesses. For patients at
risk of asthma, or with existing asthma, viral respiratory tract infections can have a profound …

High-throughput, sensitive, and accurate multiplex PCR-microsphere flow cytometry system for large-scale comprehensive detection of respiratory viruses

…, EL Beaty, PA Shult, JR Prudent, JE Gern - Journal of clinical …, 2007 - Am Soc Microbiol
Human respiratory viruses are a diverse group of pathogens composed of hundreds of virus
strains, and this presents a major challenge for diagnostic laboratories. To efficiently detect …

[HTML][HTML] Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations

…, A Heinzmann, SE Wenzel, WW Busse, JE Gern… - Nature …, 2011 - ncbi.nlm.nih.gov
Asthma is a common disease with a complex risk architecture including both genetic and
environmental factors. We performed a meta-analysis of North American genome-wide …

Early identification of atopy in the prediction of persistent asthma in children

…, A Bush, A Custovic, PA Eigenmann, JE Gern… - The Lancet, 2008 - thelancet.com
The long-term solution to the asthma epidemic is thought to be prevention, and not treatment
of established disease. Atopic asthma arises from gene–environment interactions, which …

Role of viral infections in the development and exacerbation of asthma in children

T Jartti, JE Gern - Journal of allergy and clinical immunology, 2017 - Elsevier
… JE Gern has received a grant from the National Institutes of Health/National Institutes of
Allergy and Infectious Disease; has consultant arrangements with Janssen, Regeneron, and …

Association of respiratory allergy, asthma, and expression of the SARS-CoV-2 receptor ACE2

…, PJ Gergen, P Becker, A Togias, JE Gern… - Journal of Allergy and …, 2020 - jacionline.org
SARS-CoV-2 uses angiotensin-converting enzyme 2 (ACE2) as its cellular receptor, as do
SARS-CoV and the coronavirus NL63. 1 Higher ACE2 expression increases in vitro …

Rhinovirus illnesses during infancy predict subsequent childhood wheezing

…, TE Pappas, DF DaSilva, CJ Tisler, JE Gern - Journal of Allergy and …, 2005 - Elsevier
BACKGROUND: The contribution of viral respiratory infections during infancy to the development
of subsequent wheezing and/or allergic diseases in early childhood is not established. …

[HTML][HTML] The infant nasopharyngeal microbiome impacts severity of lower respiratory infection and risk of asthma development

…, YA Bochkov, K Grindle, SL Johnston, JE Gern… - Cell host & …, 2015 - cell.com
The nasopharynx (NP) is a reservoir for microbes associated with acute respiratory
infections (ARIs). Lung inflammation resulting from ARIs during infancy is linked to asthma …