Resistance to chemotherapy remains a significant obstacle in the treatment of hormone-
independent breast cancer. Recent evidence suggests that altered sphingolipid signaling …

BACKGROUND Little is known about the clinical factors associated with COVID‐19 disease
severity in children and adolescents. METHODS We conducted a retrospective cohort study …

Alterations in sphingolipid metabolism have been shown to contribute to the development of
endocrine resistance and breast cancer tumor survival. Sphingosine kinase (SK), in …

BACKGROUND Little is known about the epidemiology and outcomes of neurologic
complications associated with coronavirus disease 2019 (COVID-19) in children. METHODS We …

Background Adult human mesenchymal stem cells (hMSC) have been shown to home to
sites of carcinoma and affect biological processes, including tumour growth and metastasis. …

Adult human mesenchymal stem cells (hMSCs) have been shown to home to sites of breast
cancer and integrate into the tumor stroma. We demonstrate here the effect of hMSCs on …

The impact of COVID‐19 public health interventions on pediatric illnesses nationwide is
unknown. We performed a multicenter, cross‐sectional study of encounters at 44 children's …

… Antoon, MD, PhD … Drs Antoon, Potisek, and Lohr have disclosed no financial
relationships relevant to this article. This commentary does not contain a discussion of an …

Background/Objectives Stevens‐Johnson syndrome ( SJS ) and toxic epidermal necrolysis (
TEN ) are life‐threatening cutaneous reactions, typically to drugs or infection. The incidence …

Objective To review the relevant literature related to children with reported penicillin allergy
and highlight the different ways in which children could be delabeled and to evaluate the …