PURPOSE Knee osteoarthritis is a common, debilitating chronic disease. Prolotherapy is an
injection therapy for chronic musculoskeletal pain. We conducted a 3-arm, blinded (injector, …

Prolotherapy is an alternative injection‐based therapy for chronic musculoskeletal pain. Three
different proliferants, D‐glucose (dextrose), phenol‐glucose‐glycerine (P2G), and sodium …

Background Prolotherapy is an alternative therapy for chronic musculoskeletal injury
including joint laxity. The commonly used injectant, D-glucose (dextrose), is hypothesized to …

Objective: The objective of this study was to determine whether prolotherapy, an injection-based
complementary treatment for chronic musculoskeletal conditions, improves pain, …

… Author links open overlay panel David Rabago MD a , Richard Kijowski MD b , Michael
Woods MD b , Jeffrey J. Patterson DO b , Marlon Mundt PhD a , Aleksandra Zgierska MD, PhD a , …

Based on the study of 67 affected women during a period of 15 years, we report the clinical
features and natural history of focal vulvitis, a unique syndrome characterized by severe and …

BACKGROUND, Little is known about substance use and substance use disorders among
primary care patients with chronic back pain. This study compared groups of patients with and …

Objectives: This study determined whether injection with hypertonic dextrose and morrhuate
sodium (prolotherapy) using a pragmatic, clinically determined injection schedule for knee …

Background: Eleven percent of American adults have chronic low back pain—and many of
these individuals have severe, disabling, refractory pain. Many texts recommend against …

The November 2012 article by Van Manen and colleagues1 on the management of knee
osteoarthritis (OA) provides a useful update of several therapies. However, numerous …