Pancreatic ductal adenocarcinoma (PDAC) carries a dismal prognosis and lacks a human
cell model of early disease progression. When human PDAC cells are injected into …

Background: Primary care physicians (PCPs) are optimally situated to identify and manage
early stage chronic kidney disease (CKD). Nonetheless, studies have documented …

Clinically detectable thyroid nodules are less common in children than adults. However,
they are associated with an increased risk of malignancy. Therefore, thorough evaluation of …

Aims Determine incidence, prevalence and mortality of Type 1 diabetes (T1D) in children
and youth <25 years (y) in Mali during the first 10 years of the Santé Diabète/Life for a Child …

Background. The engagement of patients/individuals and/or communities has become
increasingly important in all aspects of the research process. Objective. The aim of this …

X‐linked hypophosphataemia (XLH), the most common inherited form of rickets, is caused
by a PHEX gene mutation that leads to excessive serum levels of fibroblast growth factor 23 (…

… Author links open overlay panel Jessica L. Sandy a b , Carlos Nunez c d , Benjamin J.
Wheeler e , Craig Jefferies f , Anne Morris c d , Aris Siafarikas g h i , Christine P. Rodda j k , Peter …

OBJECTIVE To compare demographic, clinical, and therapeutic characteristics of children
with type 1 diabetes age <6 years across three international registries: Diabetes Prospective …

Background. Community engagement in research is essential for translating the best
evidence into community and clinical practice to improve the health and well-being of the …

Bruck syndrome is a rare collagen disorder with autosomal recessive inheritance caused by
pathogenic variants in either FKBP10 or PLOD2 genes. It is characterized by bone fragility …