Global prevalence of antibiotic resistance in paediatric urinary tract infections caused by Escherichia coli and association with routine use of antibiotics in primary care …

A Bryce, AD Hay, IF Lane, HV Thornton, M Wootton… - bmj, 2016 - bmj.com
Objectives To systematically review studies investigating the prevalence of antibiotic resistance
in urinary tract infections caused by Escherichia coli in children and, when appropriate, …

Evaluation of current methods for detection of staphylococci with reduced susceptibility to glycopeptides

…, A Qwärnström, P Ho, M Wootton… - Journal of clinical …, 2001 - Am Soc Microbiol
The sensitivity and specificity of seven methods (agar dilution, broth microdilution, Etest at
0.5 and 2.0 McFarland (McF) inocula, two agar screening methods, and population studies [PS…

[HTML][HTML] C-reactive protein testing to guide antibiotic prescribing for COPD exacerbations

…, R Lowe, E Thomas-Jones, M Wootton… - … England Journal of …, 2019 - Mass Medical Soc
Background Point-of-care testing of C-reactive protein (CRP) may be a way to reduce
unnecessary use of antibiotics without harming patients who have acute exacerbations of chronic …

A Multicenter Study Evaluating the Current Strategies for Isolating Staphylococcus aureus Strains with Reduced Susceptibility to Glycopeptides

M Wootton, AP MacGowan, TR Walsh… - Journal of clinical …, 2007 - Am Soc Microbiol
Glycopeptide-intermediate Staphylococcus aureus (GISA) and heterogeneous GISA (hGISA)
strains are notoriously difficult to detect in the diagnostic laboratory. The clinical importance …

The Diagnosis of Urinary Tract infection in Young children (DUTY): a diagnostic prospective observational study to derive and validate a clinical algorithm for the …

…, CA Waldron, P Whiting, M Wootton… - Health technology …, 2016 - orca.cardiff.ac.uk
Background It is not clear which young children presenting acutely unwell to primary care
should be investigated for urinary tract infection (UTI) and whether or not dipstick testing …

Variations in presentation, management, and patient outcomes of urinary tract infection: a prospective four-country primary care observational cohort study

…, J Bates, M Lau, T Pickles, M Gal, M Wootton… - British Journal of …, 2017 - bjgp.org
Background Regional variations in the presentation of uncomplicated urinary tract infection (UTI)
and pathogen sensitivity to antibiotics have been cited as reasons to justify differences …

[HTML][HTML] Vancomycin susceptibility within methicillin-resistant Staphylococcus aureus lineages

RA Howe, A Monk, M Wootton, TR Walsh… - Emerging infectious …, 2004 - ncbi.nlm.nih.gov
Methicillin-resistant Staphylococcus aureus (MRSA) with reduced vancomycin susceptibility
(VISA, vancomycin-intermediate S. aureus) has been reported from many countries. …

Evaluation of a New Etest Vancomycin-Teicoplanin Strip for Detection of Glycopeptide-Intermediate Staphylococcus aureus (GISA), in Particular, Heterogeneous …

…, L Bylund, P Vidh, K Mills, M Wootton… - Journal of clinical …, 2008 - Am Soc Microbiol
Glycopeptide-intermediate Staphylococcus aureus (GISA) and, in particular, heterogeneous
GISA (hGISA) are difficult to detect by standard MIC methods, and thus, an accurate …

[HTML][HTML] Identification of clinical and urine biomarkers for uncomplicated urinary tract infection using machine learning algorithms

…, M Eberl, N Topley, I Weeks, S Cuff, M Wootton… - Scientific reports, 2019 - nature.com
Women with uncomplicated urinary tract infection (UTI) symptoms are commonly treated
with empirical antibiotics, resulting in overuse of antibiotics, which promotes antimicrobial …

[HTML][HTML] Faecal carriage of antibiotic resistant Escherichia coli in asymptomatic children and associations with primary care antibiotic prescribing: a systematic review …

A Bryce, C Costelloe, C Hawcroft, M Wootton… - BMC infectious …, 2016 - Springer
Background The faecal reservoir provides optimal conditions for the transmission of
resistance genes within and between bacterial species. As key transmitters of infection within …