[HTML][HTML] Can machine-learning improve cardiovascular risk prediction using routine clinical data?
Background Current approaches to predict cardiovascular risk fail to identify many people
who would benefit from preventive treatment, while others receive unnecessary intervention. …
who would benefit from preventive treatment, while others receive unnecessary intervention. …
[HTML][HTML] Achieving change in primary care—causes of the evidence to practice gap: systematic reviews of reviews
Background This study is to identify, summarise and synthesise literature on the causes of
the evidence to practice gap for complex interventions in primary care. Design This study is a …
the evidence to practice gap for complex interventions in primary care. Design This study is a …
[HTML][HTML] Family history of type 2 diabetes: a population-based screening tool for prevention?
Purpose: To evaluate the use of self-reported family medical history as a potential screening
tool to identify people at-risk for diabetes. Methods: The HealthStyles 2004 mail survey …
tool to identify people at-risk for diabetes. Methods: The HealthStyles 2004 mail survey …
Family history in public health practice: a genomic tool for disease prevention and health promotion
Family history is a risk factor for many chronic diseases, including cancer, cardiovascular
disease, and diabetes. Professional guidelines usually include family history to assess health …
disease, and diabetes. Professional guidelines usually include family history to assess health …
[HTML][HTML] The comorbidity burden of type 2 diabetes mellitus: patterns, clusters and predictions from a large English primary care cohort
Background The presence of additional chronic conditions has a significant impact on the
treatment and management of type 2 diabetes (T2DM). Little is known about the patterns of …
treatment and management of type 2 diabetes (T2DM). Little is known about the patterns of …
Achieving change in primary care—effectiveness of strategies for improving implementation of complex interventions: systematic review of reviews
Objective To identify, summarise and synthesise available literature on the effectiveness of
implementation strategies for optimising implementation of complex interventions in primary …
implementation strategies for optimising implementation of complex interventions in primary …
[HTML][HTML] HEART UK consensus statement on Lipoprotein (a): A call to action
Lipoprotein(a), Lp(a), is a modified atherogenic low-density lipoprotein particle that contains
apolipoprotein(a). Its levels are highly heritable and variable in the population. This …
apolipoprotein(a). Its levels are highly heritable and variable in the population. This …
The 'new genetics' and primary care: GPs' views on their role and their educational needs
Background. Given the limited specialist resources available to cope with the rising demand
for genetic services, it has been proposed that at least some of these services are provided …
for genetic services, it has been proposed that at least some of these services are provided …
[HTML][HTML] Using family history information to promote healthy lifestyles and prevent diseases; a discussion of the evidence
…, ACJW Janssens, M Wijdenes-Pijl, N Qureshi… - BMC public health, 2010 - Springer
Background A family history, reflecting genetic susceptibility as well as shared environmental
and behavioral factors, is an important risk factor for common chronic multifactorial …
and behavioral factors, is an important risk factor for common chronic multifactorial …
[HTML][HTML] Sub-optimal cholesterol response to initiation of statins and future risk of cardiovascular disease
Objective To assess low-density lipoprotein cholesterol (LDL-C) response in patients after
initiation of statins, and future risk of cardiovascular disease (CVD). Methods Prospective …
initiation of statins, and future risk of cardiovascular disease (CVD). Methods Prospective …