Apoptosis of osteocytes in glucocorticoid-induced osteonecrosis of the hip

RS Weinstein, RW Nicholas… - The Journal of Clinical …, 2000 - academic.oup.com
An increase in osteoblast and osteocyte apoptosis has been demonstrated in mice and
humans receiving glucocorticoids and may be involved in the pathogenesis of the associated …

Bone metastasis: mechanisms and therapeutic opportunities

LJ Suva, C Washam, RW Nicholas… - Nature Reviews …, 2011 - nature.com
The skeleton is one of the most common sites for metastatic cancer, and tumors arising from
the breast or prostate possess an increased propensity to spread to this site. The growth of …

Associations of disease-modifying therapies with COVID-19 severity in multiple sclerosis

…, D Brum, MF Mendes, RN Alonso, RS Nicholas… - Neurology, 2021 - AAN Enterprises
Background and Objectives People with multiple sclerosis (MS) are a vulnerable group for
severe coronavirus disease 2019 (COVID-19), particularly those taking immunosuppressive …

Expression of Interleukin 8 and not Parathyroid Hormone-related Protein by Human Breast Cancer Cells Correlates with Bone Metastasis in Vivo

…, T Mon-Foote, NS Akel, RA Skinner, RW Nicholas… - Cancer research, 2002 - AACR
Metastasis is the process by which tumor cells spread from their site of origin to distant sites
after gaining access to the circulatory system. An understanding of the factors contributing to …

Comparative evaluation of local control strategies in localized Ewing sarcoma of bone: a report from the Children's Oncology Group

…, J Dormans, RC Shamberger, S Sailer, RW Nicholas… - Cancer, 2015 - Wiley Online Library
BACKGROUND Patients with Ewing sarcoma require local primary tumor control with surgery,
radiation, or both. The optimal choice of local control for overall and local disease control …

The snowboarder's foot and ankle

…, J Mastrangelo, RA Nicholas - … American journal of …, 1998 - journals.sagepub.com
We undertook a prospective study to determine the type and distribution of foot and ankle
snowboarding injuries. Reports of 3213 snowboarding injuries were collected from 12 …

Breast cancer metastasis to bone: it is not all about PTHrP

M Bendre, D Gaddy, RW Nicholas… - … and Related Research®, 2003 - journals.lww.com
Breast cancer shows a predilection for metastasis to bone. Interestingly, approximately 80%
of patients with breast cancer also have bone metastases develop at some point during the …

The cortical damage, early relapses, and onset of the progressive phase in multiple sclerosis

A Scalfari, C Romualdi, RS Nicholas, M Mattoscio… - Neurology, 2018 - AAN Enterprises
Richard Nicholas: study concept and design, analysis and interpretation of data, drafting/revising
the manuscript, critical revision of the manuscript for important intellectual content. …

Updated results of the COVID-19 in MS global data sharing initiative: anti-CD20 and other risk factors associated with COVID-19 severity

…, M Magyari, RN Alonso, RS Nicholas… - Neurology …, 2022 - AAN Enterprises
Background and Objectives Certain demographic and clinical characteristics, including the
use of some disease-modifying therapies (DMTs), are associated with severe acute …

[HTML][HTML] Kinetic analysis of the translocator protein positron emission tomography ligand [18F]GE-180 in the human brain

…, AP Goldstone, DJ Brooks, RS Nicholas… - European journal of …, 2016 - Springer
Purpose PET can image neuroinflammation by targeting the translocator protein (TSPO),
which is upregulated in activated microglia. The high nonspecific binding of the first-generation …