[HTML][HTML] Irisin inhibits hepatic cholesterol synthesis via AMPK-SREBP2 signaling

H Tang, R Yu, S Liu, B Huwatibieke, Z Li, W Zhang - EBioMedicine, 2016 - thelancet.com
Irisin, a myokine released during exercise, promotes browning of subcutaneous adipose
tissue and regulates energy homeostasis. Although exercise constantly reduces blood …

Cardioprotective effects of gypenoside XVII against ischemia/reperfusion injury: Role of endoplasmic reticulum stress, autophagy, and mitochondrial fusion fission …

S Su, J Wang, J Wang, R Yu, L Sun… - Phytotherapy …, 2022 - Wiley Online Library
Gypenoside XVII (GP‐17), a tetracyclic triterpene saponin isolated from the functional food
Gynostemma pentaphyllum, has been demonstrated protective effects against …

Haploidentical versus matched donor stem cell transplantation for patients with hematological malignancies: a systemic review and meta-analysis

B Yang, R Yu, L Cai, B Guo, H Chen, H Zhang… - Bone marrow …, 2019 - nature.com
We compared the safety and efficacy of haploidentical stem cell transplantation (haplo-SCT)
to matched donor SCT (matched-SCT) in treating hematological malignancies. The Medline…

Psoralen induces hepatic toxicity through PERK and ATF6 related ER stress pathways in HepG2 cells

Y Yu, R Yu, W Men, P Zhang, Y Zhang… - Toxicology …, 2020 - Taylor & Francis
Psoralen has potential hepatotoxicity and has a certain promoting effect on the clinical liver
injury of Psoralea corylifolia L (Fructus Psoraleae). This study investigated the underlying …

[HTML][HTML] Long-term exposure of psoralen and isopsoralen induced hepatotoxicity and serum metabolites profiles changes in female rats

Y Yu, P Wang, R Yu, J Lu, M Jiang, K Zhou - Metabolites, 2019 - mdpi.com
Pre-clinical safety evaluation of traditional medicines is imperative because of the universality
of drug-induced adverse reactions. Psoralen and isopsoralen are the major active …

[HTML][HTML] Prevalence of the GJB2 IVS1+1G >A mutation in Chinese hearing loss patients with monoallelic pathogenic mutation in the coding region of GJB2

Y Yuan, F Yu, G Wang, S Huang, R Yu, X Zhang… - Journal of translational …, 2010 - Springer
Background Mutations in the GJB2 gene are the most common cause of nonsyndromic
recessive hearing loss in China. In about 6% of Chinese patients with severe to profound …

Excess free fructose beverages and allergy in children and adolescents: Results from NHANES 2005-2006

R Yu, B Yang, L Cai, X Lu… - The Annals of Family …, 2018 - Annals Family Med
PURPOSE Our purpose was to investigate the relationship between intake of excess free
fructose beverages and allergy among children and adolescents. METHODS We analyzed …

Efficacy of cytokine-induced killer cell infusion as an adjuvant immunotherapy for hepatocellular carcinoma: a systematic review and meta-analysis

R Yu, B Yang, X Chi, L Cai, C Liu, L Yang… - Drug design …, 2017 - Taylor & Francis
This study was designed to evaluate the efficacy and safety of cytokine-induced killer (CIK)
cell-based immunotherapy as an adjuvant therapy for hepatocellular carcinoma (HCC). …

HDAC5-mTORC1 interaction in differential regulation of ghrelin and nucleobindin 2 (NUCB2)/nesfatin-1

L Ma, H Tang, Y Yin, R Yu, J Zhao, Y Li… - Molecular …, 2015 - academic.oup.com
Sodium valporate (VPA), a broad-spectrum inhibitor of histone deacetylases (HDACs),
increased ghrelin whereas decreased nesfatin-1 in mice fed normal chow diet or high-fat diet. …

mTOR signaling in X/A‐like cells contributes to lipid homeostasis in mice

Z Li, R Yu, W Yin, Y Qin, L Ma, M Mulholland… - …, 2019 - Wiley Online Library
Gastric mechanistic target of rapamycin (mTOR) signaling is inversely associated with the
expression and secretion of ghrelin, a 28‐aa peptide hormone produced by gastric X/A‐like …