Background Smoking is the leading preventable cause of illness and premature death worldwide.
Some medications have been proven to help people to quit, with three licensed for this …

Objective To systematically review studies quantifying the associations of long term (clinic),
mid-term (home), and short term (ambulatory) variability in blood pressure, independent of …

Big data abound in microbiology, but the workflows designed to enable researchers to interpret
data can constrain the biological questions that can be asked. Five years after anvi’o was …

Background Primary care is the main source of health care in many health systems, including
the UK National Health Service (NHS), but few objective data exist for the volume and …

Eating disorders are complex illnesses that are affecting adolescents with increasing frequency
[1]. They rank as the third most common chronic illness in adolescent females, with an …

Objective To clarify associations of fish consumption and long chain omega 3 fatty acids with
risk of cerebrovascular disease for primary and secondary prevention. Design Systematic …

In multiple sclerosis, partial remyelination is conspicuous in many lesions, but widespread
and lasting myelin repair ultimately fails as disability and handicap accumulate. Thus far, the …

The SARS-CoV-2 main protease (3CLpro) has an indispensable role in the viral life cycle
and is a therapeutic target for the treatment of COVID-19. The potential of 3CLpro-inhibitors to …

Multiple models describe the formation and evolution of distinct microbial phylogenetic
groups. These evolutionary models make different predictions regarding how adaptive alleles …

Objectives Surveys in various countries suggest 17% to 80% of doctors prescribe ‘placebos’
in routine practice, but prevalence of placebo use in UK primary care is unknown. Methods …