Early lactate-guided therapy in intensive care unit patients: a multicenter, open-label, randomized controlled trial

…, AP Lima, SP Willemsen… - American journal of …, 2010 - atsjournals.org
Rationale: It is unknown whether lactate monitoring aimed to decrease levels during initial
treatment in critically ill patients improves outcome. Objectives: To assess the effect of lactate …

Disease activity of rheumatoid arthritis during pregnancy: results from a nationwide prospective study

…, FE Van De Geijn, SP Willemsen… - Arthritis Care & …, 2008 - Wiley Online Library
Objective According to common knowledge and retrospective studies, approximately 75–90%
of patients with rheumatoid arthritis (RA) will improve during pregnancy. Prospective data …

[HTML][HTML] Immunoglobulin G galactosylation and sialylation are associated with pregnancy-induced improvement of rheumatoid arthritis and the postpartum flare …

…, M Wuhrer, MHJ Selman, SP Willemsen… - Arthritis research & …, 2009 - Springer
Introduction Improvement of rheumatoid arthritis (RA) during pregnancy has been causatively
associated with increased galactosylation of immunoglobulin G (IgG) N-glycans. Since …

Association of higher rheumatoid arthritis disease activity during pregnancy with lower birth weight: results of a national prospective study

…, H van der Heide, SP Willemsen… - … : Official Journal of …, 2009 - Wiley Online Library
Objective To determine the outcome of pregnancy in women with rheumatoid arthritis (RA)
in relation to disease activity and medication use during the pregnancy. Methods In a …

Procalcitonin-guided decision making for duration of antibiotic therapy in neonates with suspected early-onset sepsis: a multicentre, randomised controlled trial …

…, RF Kornelisse, J van Gijsel, EG Visser, SP Willemsen… - The Lancet, 2017 - thelancet.com
Background Up to 7% of term and late-preterm neonates in high-income countries receive
antibiotics during the first 3 days of life because of suspected early-onset sepsis. The …

Supervised exercise therapy versus usual care for patellofemoral pain syndrome: an open label randomised controlled trial

…, MY Berger, EM Heintjes, JAN Verhaar, SP Willemsen… - Bmj, 2009 - bmj.com
Objective To assess the effectiveness of supervised exercise therapy compared with usual
care with respect to recovery, pain, and function in patients with patellofemoral pain syndrome…

Air pollution exposure during pregnancy, ultrasound measures of fetal growth, and adverse birth outcomes: a prospective cohort study

…, Y de Kluizenaar, SP Willemsen… - Environmental …, 2012 - ehp.niehs.nih.gov
Background: Air pollution exposure during pregnancy might have trimester-specific effects
on fetal growth. Objective: We prospectively evaluated the associations of maternal air …

A comparative study of software programmes for cross‐sectional skeletal muscle and adipose tissue measurements on abdominal computed tomography scans of …

…, JWA Burger, SP Willemsen… - Journal of cachexia …, 2017 - Wiley Online Library
Background The association between body composition (eg sarcopenia or visceral obesity)
and treatment outcomes, such as survival, using single‐slice computed tomography (CT)‐…

Effect of glucosamine sulfate on hip osteoarthritis: a randomized trial

…, EJ Uitterlinden, EH Garling, SP Willemsen… - Annals of Internal …, 2008 - acpjournals.org
Background: The effectiveness of glucosamine sulfate as a symptom and disease modifier
for osteoarthritis is still under debate. Objective: To assess whether glucosamine sulfate has …

Association between galactosylation of immunoglobulin G and improvement of rheumatoid arthritis during pregnancy is independent of sialylation

…, AM Deelder, JMW Hazes, SP Willemsen… - Journal of proteome …, 2013 - ACS Publications
Rheumatoid arthritis (RA) is known to improve during pregnancy and to flare after delivery.
Changes in the glycosylation of immunoglobulin G (IgG)’s fragment crystallizable (Fc) have …