Background Although it is generally accepted that lowering elevated serum levels of low-density
lipoprotein (LDL) cholesterol in patients with coronary heart disease is beneficial, there …

Description: The American College of Physicians (ACP) developed this guideline to present
the evidence and provide clinical recommendations on noninvasive treatment of low back …

Background The effectiveness of surgery versus observation for men with localized prostate
cancer detected by means of prostate-specific antigen (PSA) testing is not known. Methods …

Objective: To examine the association between registered nurse (RN) staffing and patient
outcomes in acute care hospitals. Study Selection: Twenty-eight studies reported adjusted …

… Additional background material reviewed by the guideline panel included the 2007
systematic evidence review by Wilt and colleagues (6) and the 2004 Agency for Healthcare …

The National Kidney Foundation’s Kidney Disease Outcomes Quality Initiative (KDOQI) has
provided evidence-based guidelines for all stages of chronic kidney disease (CKD) and …

Prostate cancer is a common malignancy in men and the worldwide burden of this disease is
rising. Lifestyle modifications such as smoking cessation, exercise, and weight control offer …

Background: The comparative effectiveness of localized prostate cancer treatments is largely
unknown. Purpose: To compare the effectiveness and harms of treatments for localized …

Background Benign prostatic hyperplasia (BPH) is a nonmalignant enlargement of the
prostate, which can lead to obstructive and irritative lower urinary tract symptoms (LUTS). The …

Objective.— To conduct a systematic review and, where possible, quantitative meta-analysis
of the existing evidence regarding the therapeutic efficacy and safety of the saw palmetto …