The wide adoption of electronic health record systems in health care generates big real-world
data that open new venues to conduct clinical research. As a large amount of valuable …

Most of the research effort regarding asthma has been devoted to its causes, therapy, and
prognosis. There is also evidence that the presence of asthma can influence patients' …

BACKGROUND: Individuals with asthma have been reported to be at increased risk of
invasive pneumococcal disease (IPD). These findings need to be confirmed in a different …

Socioeconomic status (SES) has been associated with many health outcomes. Commonly
used datasets such as medical records often lack data on SES but do include address …

Exclusion of special populations (older adults; pregnant women, children, and adolescents;
individuals of lower socioeconomic status and/or who live in rural communities; people from …

Background Socioeconomic status (SES) is an important determinant of health, but SES
measures are frequently unavailable in commonly used datasets. Area-level SES measures are …

Objectives: Celiac disease (CD) is a common immune-mediated disorder that affects up to 1%
of the general population. Recent reports suggest that the incidence of CD has reached a …

Objective To determine the association between asthma and proinflammatory conditions.
Participants and Methods This population-based retrospective matched cohort study enrolled …

Objective To assess primary care adherence to 2007 US asthma guidelines. Patients and
Methods Patients with persistent asthma aged 5 to 65 years from 22 primary care participating …

Background: Subclinical hypothyroidism (SCH) has been associated with increased risk of
adverse pregnancy outcomes in some, but not all, studies. Uncertainty remains regarding the …