[HTML][HTML] Atopic dermatitis: diagnosis and treatment

W Frazier, N Bhardwaj - American family physician, 2020 - aafp.org
Atopic dermatitis (atopic eczema) is a chronic relapsing and remitting inflammatory skin
disease affecting one in 10 people in their lifetime. Atopic dermatitis is caused by a complex …

Staphylococcus aureus and atopic dermatitis: a complex and evolving relationship

JA Geoghegan, AD Irvine, TJ Foster - Trends in microbiology, 2018 - cell.com
Staphylococcus aureus is frequently isolated from the skin of atopic dermatitis (AD) patients
during flares. The normal microbiota is disrupted and the diversity of the microorganisms on …

[HTML][HTML] IL-4Rα blockade by dupilumab decreases Staphylococcus aureus colonization and increases microbial diversity in atopic dermatitis

C Callewaert, T Nakatsuji, R Knight, T Kosciolek… - Journal of Investigative …, 2020 - Elsevier
Dupilumab is a fully human antibody to interleukin-4 receptor α that improves the signs and
symptoms of moderate to severe atopic dermatitis (AD). To determine the effects of …

[HTML][HTML] The infectious complications of atopic dermatitis

V Wang, J Boguniewicz, M Boguniewicz… - Annals of Allergy, Asthma …, 2021 - Elsevier
Objective Atopic dermatitis (AD) is a chronic inflammatory skin disease that is complicated
by an increased risk for skin and systemic infections. Preventive therapy for AD is based on …

Risk of infection in patients with atopic dermatitis treated with dupilumab: a meta-analysis of randomized controlled trials

P Fleming, AM Drucker - Journal of the American Academy of Dermatology, 2018 - Elsevier
Background Atopic dermatitis (AD) is characterized by skin barrier defects, T helper type 2
cell activation, and increased risk for cutaneous and extracutaneous infections. In clinical …

[HTML][HTML] Recent developments and advances in atopic dermatitis: a focus on epidemiology, pathophysiology, and treatment in the pediatric setting

LF Eichenfield, S Stripling, S Fung, A Cha, A O'Brien… - Pediatric Drugs, 2022 - Springer
Atopic dermatitis (AD) is a chronic inflammatory skin disorder that affects a substantial
number of children and has a significant negative impact on affected patients and their …

Insights into atopic dermatitis gained from genetically defined mouse models

S Nakajima, T Nomura, J Common… - Journal of Allergy and …, 2019 - Elsevier
Atopic dermatitis (AD) is characterized by severe pruritus and recurrent eczema with a
chronic disease course. Impaired skin barrier function, hyperactivated TH 2 cell–type …

Structure–activity relationship studies of small molecule modulators of the staphylococcal accessory gene regulator

AR Horswill, CP Gordon - Journal of Medicinal Chemistry, 2019 - ACS Publications
The accessory gene regulator (agr) quorum-sensing system is arguably the most important
regulator of Staphylococcus virulence. The agr-system serves a crucial role in pathogenesis …

[HTML][HTML] Taiwanese Dermatological Association consensus for the management of atopic dermatitis: A 2020 update

TC Chan, NL Wu, LS Wong, YT Cho, CY Yang… - Journal of the Formosan …, 2021 - Elsevier
Background/Purpose Atopic dermatitis (AD) is a chronic inflammatory disease commonly
seen in children and increasingly recognized in adults. With recent advances in the …

[HTML][HTML] Fully supercritical CO2 preparation of a nanostructured MOF composite with application in cutaneous drug delivery

M Kubovics, S Rojas, AM Lopez, J Fraile… - The Journal of …, 2021 - Elsevier
Abstract Supercritical CO 2 (scCO 2) technology is used here as an efficient method to assist
in the preparation of a cutaneous polymeric formulation based on drug containing metal …