Approaches for discontinuation versus continuation of long‐term antidepressant use for depressive and anxiety disorders in adults

E Van Leeuwen, ML van Driel… - Cochrane Database …, 2021 - cochranelibrary.com
Background Depression and anxiety are the most frequent indication for which
antidepressants are prescribed. Long‐term antidepressant use is driving much of the …

[HTML][HTML] An update on medication use in older adults: a narrative review

HE Barry, CM Hughes - Current Epidemiology Reports, 2021 - Springer
Abstract Purpose of Review The global phenomenon of population aging is impacting the
health and care needs of society. The use of medications by older adults is acknowledged to …

[HTML][HTML] Deprescribing is an essential part of good prescribing

B Farrell, D Mangin - American family physician, 2019 - aafp.org
Deprescribing Is an Essential Part of Good Prescribing | AAFP Advertisement search close
brand logo BARBARA FARRELL, PharmD, FCSHP, Bruyère Research Institute and …

[HTML][HTML] Team approach to polypharmacy evaluation and reduction: study protocol for a randomized controlled trial

D Mangin, L Lamarche, G Agarwal, HL Banh… - Trials, 2021 - Springer
Background Polypharmacy in older adults can be associated with negative outcomes
including falls, impaired cognition, reduced quality of life, and general and functional …

Association between frailty, chronic conditions and socioeconomic status in community-dwelling older adults attending primary care: a cross-sectional study using …

D Mangin, J Lawson, C Risdon, HYH Siu, T Packer… - BMJ open, 2023 - bmjopen.bmj.com
Objectives Frailty is a multidimensional syndrome of loss of reserves in energy, physical
ability, cognition and general health. Primary care is key in preventing and managing frailty …

Appropriateness of medications in older adults living with frailty: impact of a pharmacist-led structured medication review process in primary care

S Khera, M Abbasi, J Dabravolskaj… - Journal of Primary …, 2019 - journals.sagepub.com
Background: Older persons with frailty take multiple medications and are vulnerable to
inappropriate prescribing. Objective: This study assesses the impact of a team-based …

[HTML][HTML] Improving care for elderly patients living with polypharmacy: protocol for a pragmatic cluster randomized trial in community-based primary care practices in …

M Greiver, S Dahrouge, P O'Brien, D Manca… - Implementation …, 2019 - Springer
Background Elders living with polypharmacy may be taking medications that do not benefit
them. Polypharmacy can be associated with elevated risks of poor health, reduced quality of …

[HTML][HTML] A proposed curricular framework for an interprofessional approach to deprescribing

B Farrell, L Raman-Wilms, CA Sadowski… - Medical Science …, 2023 - Springer
Deprescribing involves reducing or stopping medications that are causing more harm than
good or are no longer needed. It is an important approach to managing polypharmacy, yet …

[HTML][HTML] Drug prescription profiles in patients with polypharmacy in Spain: a Large-Scale Pharmacoepidemiologic Study using real-world data

MÁ Hernández-Rodríguez, E Sempere-Verdú… - International journal of …, 2021 - mdpi.com
We aimed to identify and compare medication profiles in populations with polypharmacy
between 2005 and 2015. We conducted a cross-sectional study using information from the …

Drug stewardship in chronic kidney disease to achieve effective and safe medication use

RK Hall, R Kazancıoğlu, T Thanachayanont… - Nature Reviews …, 2024 - nature.com
People living with chronic kidney disease (CKD) often experience multimorbidity and require
polypharmacy. Kidney dysfunction can also alter the pharmacokinetics and …