BACKGROUND Although rapid diagnosis of Lyme disease is essential for effective
treatment, there is concern about inappropriate testing. We conducted a prospective, cross …

Objectives Lyme disease (LD) incidence is increasing, but data suggest some clinicians are
not fully aware of recommended procedures for ordering and interpreting diagnostic tests …

1194 CMAJ, November 3, 2015, 187 (16) quence, patients and physicians should be
cautious in choosing a referral laboratory in the US when seeking “second opinion” serology …

There is much confusion and misinformation about the diagnosis of Lyme disease, as well
as its treatment. This review explains why one cannot make a correct diagnosis of Lyme …

Testing for Lyme disease is challenging and if done incorrectly can lead to unnecessary
treatment. To interpret serologic test results, first assess the patient's pretest probability of …

The use of serologic testing and its value in the diagnosis of Lyme disease remain confusing
and controversial for physicians, especially concerning persons who are at low risk for the …

High demand undoubtedly has provided a potent stimulus for the development and
marketing of a large number of assays for detection of antibody to Borrelia burgdorferi. As …

Background Lyme disease is on the rise in Canada. It is a notifiable disease, and when
infection is disseminated, serological testing provides supplemental evidence to confirm a …

Objective The purpose of this paper is to review information regarding the current guidelines
for the clinical laboratory diagnosis of Lyme disease as set forth by the Centers for Disease …

Recent guidelines established by the Association of State and Territorial Public Health
Laboratory Directors (ASTPHLD) and the US Centers for Disease Control and Prevention …