Considerations before selecting a stepped-wedge cluster randomized trial design for a practice improvement study

AM Nguyen, CM Cleland, LM Dickinson… - The Annals of Family …, 2022 - Annals Family Med
PURPOSE Despite the growing popularity of stepped-wedge cluster randomized trials (SW-
CRTs) for practice-based research, the design's advantages and challenges are not well …

Variations in stepped-wedge cluster randomized trial design: insights from the patient-centered care transitions in heart failure trial

RR Unni, SF Lee, L Thabane, S Connolly… - American heart …, 2020 - Elsevier
The stepped-wedge (SW) cluster randomized controlled trial, in which clusters cross over in
a randomized sequence from control to intervention, is ideal for the implementation and …

Systematic review of stepped wedge cluster randomized trials shows that design is particularly used to evaluate interventions during routine implementation

ND Mdege, MS Man, CA Taylor… - Journal of clinical …, 2011 - Elsevier
OBJECTIVE: To describe the application of the stepped wedge cluster randomized
controlled trial (CRCT) design. STUDY DESIGN AND SETTING: Systematic review. We …

Recruitment and implementation challenges were common in stepped-wedge cluster randomized trials: Results from a methodological review

A Caille, M Taljaard, F Le Vilain—Abraham… - Journal of Clinical …, 2022 - Elsevier
Objective To explore challenges in recruitment and intervention implementation in recent
stepped-wedge cluster randomized trials (SW-CRTs). Study Design and Setting We …

Cluster-randomized controlled trials evaluating complex interventions in general practices are mostly ineffective: a systematic review

A Siebenhofer, MA Paulitsch, G Pregartner… - Journal of Clinical …, 2018 - Elsevier
Objectives The aim of this study was to evaluate how frequently complex interventions are
shown to be superior to routine care in general practice-based cluster-randomized …

Adherence to key recommendations for design and analysis of stepped-wedge cluster randomized trials: A review of trials published 2016–2022

P Nevins, M Ryan, K Davis-Plourde, Y Ouyang… - Clinical …, 2023 - journals.sagepub.com
Background/Aims The stepped-wedge cluster randomized trial (SW-CRT), in which clusters
are randomized to a time at which they will transition to the intervention condition–rather …

[HTML][HTML] The current use of feasibility studies in the assessment of feasibility for stepped-wedge cluster randomised trials: a systematic review

CA Kristunas, K Hemming, H Eborall, S Eldridge… - BMC medical research …, 2019 - Springer
Background Stepped-wedge cluster randomised trials (SW-CRTs) are a pragmatic trial
design, providing an unprecedented opportunity to increase the robustness of evidence …

Systematic review showed that stepped-wedge cluster randomized trials often did not reach their planned sample size

FA Eichner, RHH Groenwold, DE Grobbee… - Journal of clinical …, 2019 - Elsevier
Objective To determine how often stepped-wedge cluster randomized controlled trials reach
their planned sample size, and what reasons are reported for choosing a stepped-wedge …

Stepped wedge cluster randomized trials are efficient and provide a method of evaluation without which some interventions would not be evaluated

K Hemming, A Girling, J Martin, SJ Bond - Journal of clinical …, 2013 - jclinepi.com
The stepped wedge design is a new type of randomized controlled trial (RCT), which is
increasingly being used, especially in the evaluation of service delivery interventions (SDIs) …

Systematic review finds major deficiencies in sample size methodology and reporting for stepped-wedge cluster randomised trials

J Martin, M Taljaard, A Girling, K Hemming - BMJ open, 2016 - bmjopen.bmj.com
Background Stepped-wedge cluster randomised trials (SW-CRT) are increasingly being
used in health policy and services research, but unless they are conducted and reported to …