PURPOSE Previous studies have reported inconsistent findings regarding the association
between the use of acid-suppressive drugs such as proton pump inhibitors (PPIs) and …

AIMS: Recent studies have suggested an increased risk of fractures with proton pump
inhibitors (PPIs) and histamine-2 receptor antagonists (H2RAs). We planned to perform a …

Background Concerns have been raised about the risk of fractures with acid-suppressive
medications, such as proton pump inhibitors and histamine 2-receptor antagonists. Methods …

Objectives We aimed to clarify the nature of the association between hip fracture risk and
use of proton pump inhibitors (PPI s) or histamine2‐receptor antagonists (H2 RA s). Methods …

It remains unknown why proton pump inhibitor (PPI) use may be associated with risk of
osteoporotic fractures; evidence of direct effects on calcium absorption or on the osteoclast …

BACKGROUND & AIMS: Drugs that inhibit gastric acid might increase the risk of hip fracture.
However, little long-term exposure data exist and no large studies have been conducted in …

We studied the effect of proton pump inhibitors, histamine H 2 receptor antagonists, and
other types of antacid drugs on fracture risk. All cases were subjects with any fracture …

Recent studies have suggested an increased fracture risk with acid-suppressive medication
use. We studied two cohorts of men and women over age 65 who were enrolled in the …

Previous studies have found an association between acid suppressants and fracture risk.
We assessed fracture risk in patients taking concomitant acid suppressant and …

Background Patients with peptic ulcer disease (PUD) and gastroesophageal reflux disease
(GERD) are more likely to receive long-term therapy with proton pump inhibitors (PPIs). This …