The US opioid epidemic challenges us to rethink our understanding of the function of
opioids and the nature of chronic pain. We have neatly separated opioid use and abuse as …

The opioid systems play an important role in mediating both physical pain and negative
affects (eg, the pain of social isolation). From an evolutionary perspective, it is not surprising …

This article reviews the complexities of the opioid epidemic, considering recent research
involving the current state of the opioid epidemic; chronic pain and its role in the crisis; the …

Opioid Abuse in Chronic Pain — Misconceptions and Mitigation Strategies | NEJM Skip to main
content NEJM Group Follow Us Facebook Twitter Instagram YouTube LinkedIn Prepare to …

Addiction to opioid analgesics is an important and yet underinvestigated clinical issue,
which has substantial implications in opioid therapy for chronic pain management …

This is the sixth and final AAPM President's Message of my term. Prior messages
emphasized that pain and its treatment should be viewed not only as individual patient …

Pain has a useful protective role; through avoidance learning, it helps to decrease the
probability of engaging in tissue-damaging, or otherwise dangerous experiences. In our …

Opioid misuse and addiction have taken a massive toll on society, including lives lost,
socioeconomic disruption, financial costs, and a burden on the health care system. This has …

Pain and addiction are complex disorders with many commonalities. Beneficial outcomes for
both disorders can be achieved through similar principles such as individualized medication …

Pain is a complex experience with far-reaching organismal influences ranging from
biological factors to those that are psychological and social. Such influences can serve as …