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Annals of Family Medicine 5:328-335 (2007)
© 2007 Annals of Family Medicine, Inc.
doi: 10.1370/afm.702

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Effectiveness of a Time-Limited Cognitive Behavior Therapy–Type Intervention Among Primary Care Patients With Medically Unexplained Symptoms

Javier I. Escobar, MD1, Michael A. Gara, PhD1,2, Angelica M. Diaz-Martinez, PsyD1, Alejandro Interian, PhD1, Melissa Warman, PhD1, Lesley A. Allen, PhD1, Robert L. Woolfolk, PhD3, Eric Jahn, MD4 and Denise Rodgers, MD4

1 Department of Psychiatry, UMDNJ-Robert Wood Johnson Medical School, Piscataway, NJ
2 UMDNJ-University Behavioral Health Care, Piscataway, NJ
3 Department of Psychology, Rutgers University, Piscataway, NJ
4 Department of Internal Medicine, UMDNJ-Robert Wood Johnson Medical School, New Brunswick, NJ

CORRESPONDING AUTHOR: Javier I. Escobar, MD, Department of Psychiatry, UMDNJ-Robert Wood Johnson, Medical School, 675 Hoes Ln, Piscataway, NJ 08854-5635, escobaja{at}umdnj.edu

PURPOSE Patients seeking care for medically unexplained physical symptoms pose a major challenge at primary care sites, and there are very few well-accepted and properly evaluated interventions to manage such patients.

METHODS We tested the effectiveness of a cognitive behavior therapy (CBT)-type intervention delivered in primary care for patients with medically unexplained physical symptoms. Patients were randomly assigned to receive either the intervention plus a consultation letter or usual clinical care plus a consultation letter. Physical and psychiatric symptoms were assessed at baseline, at the end of treatment, and at a 6-month follow-up. All treatments and assessments took place at the same primary care clinic where patients sought care.

RESULTS A significantly greater proportion of patients in the intervention group had physical symptoms rated by clinicians as "very much improved" or "much improved" compared with those in the usual care group (60% vs 25.8%; odds ratio = 4.1; 95% confidence interval, 1.9–8.8; P<.001). The intervention’s effect on unexplained physical symptoms was greatest at treatment completion, led to relief of symptoms in more than one-half of the patients, and persisted months after the intervention, although its effectiveness gradually diminished. The intervention also led to significant improvements in patient-reported levels of physical symptoms, patient-rated severity of physical symptoms, and clinician-rated depression, but these effects were no longer noticeable at follow-up.

CONCLUSIONS This time-limited, CBT-type intervention significantly ameliorated unexplained physical complaints of patients seen in primary care and offers an alternative for managing these common and problematic complaints in primary care settings.

Key Words: Mental health • somatization disorder • chronic pain • pain management • health care delivery/health services research • primary care • disadvantaged • access to health care • Hispanics • Latinos • psychotherapy, brief




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TRACK Comments:

Read all TRACK Comments

Some remarks about a high-quality trial
Peter L Lucassen, et al.
Annals of Family Medicine, 2 Aug 2007 [Full text]
Response to Lucassen et al.
Javier I Escobar
Annals of Family Medicine, 16 Aug 2007 [Full text]
Treating medically-unexplained symptoms: is it still a shot in the dark?
Oye Gureje
Annals of Family Medicine, 18 Aug 2007 [Full text]
What were the perameters of your treatment for these patients?
Carolyn L. Leier
Annals of Family Medicine, 21 Aug 2008 [Full text]



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