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Research ArticleSystematic Review

Implementation and Effectiveness of Integrating Palliative Care Into Ambulatory Care of Noncancer Serious Chronic Illness: Mixed Methods Review and Meta-Analysis

Linda C. Chyr, Lyndsay DeGroot, Julie M. Waldfogel, Susan M. Hannum, Danetta H. Sloan, Valerie T. Cotter, Allen Zhang, JaAlah-Ai Heughan, Renee F. Wilson, Karen A. Robinson and Sydney M. Dy
The Annals of Family Medicine January 2022, 20 (1) 77-83; DOI: https://doi.org/10.1370/afm.2754
Linda C. Chyr
1Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland
MPH
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  • For correspondence: lchyr@jhmi.edu
Lyndsay DeGroot
2Johns Hopkins University, School of Nursing, Baltimore, Maryland
BSN, RN
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Julie M. Waldfogel
3Department of Pharmacy, Johns Hopkins Hospital, Baltimore, Maryland
PharmD, BCGP
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Susan M. Hannum
4Department of Health, Behavior and Society, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland
PhD, MA
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Danetta H. Sloan
4Department of Health, Behavior and Society, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland
PhD, MSW
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Valerie T. Cotter
2Johns Hopkins University, School of Nursing, Baltimore, Maryland
DrNP, MSN
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Allen Zhang
1Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland
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JaAlah-Ai Heughan
1Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland
MS
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Renee F. Wilson
1Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland
MS
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Karen A. Robinson
5Johns Hopkins University, School of Medicine, Baltimore, Maryland
PhD
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Sydney M. Dy
1Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland
MD, MS
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Supplemental materials in PDF file below

Supplemental Appendix 1. Methods 

Study Selection (Tables 1a-1e) 

Table 1a. PICOTS: Inclusion and exclusion criteria for quantitative studies relevant to integrating palliative care into ambulatory care for serious life-threatening chronic illness or conditions 

Table 1b. Additional inclusion and exclusion criteria for qualitative, mixed-methods, and process evaluation studies 

Table 1c: Literature Search Strategies on PubMed 

Table 1d. Minimal clinically important differences and clinical cutoff scores for outcome assessment tools included in review 

Table 1e. Definitions of the grades of overall strength of evidence 

Supplemental Appendix 2. Results 

Quantitative Studies (Tables 2a-2b) 

Supplemental Table 2a. Characteristics of effectiveness studies assessing models for integrating palliative care

Table 2b. Summary of effectiveness findings for models for integrating palliative care and multimodal interventions by outcome 

Table 2c. Characteristics of qualitative studies for models and multimodal interventions 

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