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Research ArticleOriginal Research

Patients With Type 2 Diabetes at Risk for Major Depressive Disorder Over Time

Diana M. Naranjo, Lawrence Fisher, Patricia A. Areán, Danielle Hessler and Joseph Mullan
The Annals of Family Medicine March 2011, 9 (2) 115-120; DOI: https://doi.org/10.1370/afm.1212
Diana M. Naranjo
PhD
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  • For correspondence: diana.naranjo@ucsf.edu
Lawrence Fisher
PhD
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Patricia A. Areán
PhD
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Danielle Hessler
PhD
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Joseph Mullan
PhD
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The Article in Brief

Patients With Type 2 Diabetes at Risk for Major Depressive Disorder Over Time

Diana M. Naranjo , and colleagues

Background Depression is common among patients with type 2 diabetes. This study set out to identify characteristics that predict the onset of major depressive disorder (MDD) among primary care patients with diabetes.

What This Study Found Among 338 adult patients with type 2 diabetes, researchers found prior MDD and negative affect were the primary predictors of subsequent MDD. When stratified by negative affect, negative life events, elevated body mass index, and poor control of glycated hemoglobin also predicted MDD.

Implications

  • Negative life events and patients� disease-related concerns are important when understanding what predicts MDD. The authors conclude that these variables combine to yield the negative emotional symptoms that predict MDD over time.
  • When patients have moderate levels of increased depressive symptoms, it may be helpful to inquire about other life stressors and chronic disease management. Devoting attention to these factors may have a positive impact on patients' emotional status as well as their disease management.

  View article

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