Article Figures & Data
Figures
Tables
Supplemental Appendix
Supplemental Appendix. Mean Individual Symptom Scores Reported for Study and Dosage Arm
Files in this Data Supplement:
- Supplemental data: Appendix - PDF file, 2 pages, 238 KB
The Article in Brief
Gail Hayward, and colleagues
Background Acute sinusitis is often treated with antibiotics, although there is little evidence for their benefit. This analysis of existing research examines the effects of intranasal corticosteroids on acute sinusitis symptoms.
What This Study Found After 14 to 21 days of intranasal corticosteroid use, patients show a small increase in the resolution or improvement of symptoms; the most consistently significant benefits are relief of face pain and congestion. The effect is most marked when patients are given longer durations of treatment (21 days) and higher doses of medication.
Implications
- The authors call for additional research comparing intranasal corticosteroids with placebo and without antibiotics to clarify the time-course of clinical benefit and the impact on work and quality of life.