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The Article in Brief
A Comparison of the Male Osteoporosis Risk Estimation Score (MORES) and the FRAX in Identifying Men at Risk for Osteoporosis
Alvah R. Cass , and colleagues
Background This study compares the Male Osteoporosis Risk Estimation Score (MORES) and the Fracture Risk Assessment Tool (FRAX) in screening men for osteoporosis.
What This Study Found Compared to the MORES, the FRAX under-performs as a screening strategy for osteoporosis using the threshold score suggested by the US Preventive Services Task Force. Among men aged 50 years and older, based on the MORES, 42 percent of men in the sample would be referred for a follow-up dual-energy x-ray absorptiometry (DXA) scan, of whom 10 percent had osteoporosis. In comparison, based on the FRAX, 12 percent of men would be referred for DXA, of whom 14 percent had osteoporosis. Agreement between the two screening tools was poor. When the MORES and FRAX were integrated, they identified 82 percent of men who were candidates for treatment.
Implications
- An integrated approach, which uses the MORES to identify men who should undergo a diagnostic DXA scan and the FRAX to guide treatment decisions, may be optimal.