Abstract
The purpose of this retrospective matched-cohort study was to evaluate the stability of thyroid stimulating hormone (TSH) in patients using synthetic compared with desiccated thyroid products. Patients using a thyroid product for the treatment of hypothyroidism were matched 1:1 on age, sex, race/ethnicity, and had a follow-up period of 3 years after the index date. The primary outcome was percent of in-range TSH values. Over 3 years, TSH values in both groups were in-range 79% of the time (P = 0.905). Our results showed no difference in longitudinal TSH stability between desiccated thyroid products and synthetic levothyroxine.
- thyroid stimulating hormone (TSH)
- levothyroxine
- desiccated thyroid
- stability
- hypothyroidism
- thyrotropin, thyroxine, thyroid (USP)
- Received for publication December 6, 2018.
- Revision received December 13, 2019.
- Accepted for publication December 17, 2019.
- © 2020 Annals of Family Medicine, Inc.