Prevalence and Predictors of Night Sweats, Day Sweats, and Hot Flashes in Older Primary Care Patients: An OKPRN Study

Abstract

PURPOSE We wanted to estimate the prevalence of night sweats, day sweats, and hot flashes in older primary care patients and identify associated factors.

METHODS We undertook a cross-sectional study of patients older than 64 years recruited from the practices of 23 family physicians. Variables included sociodemographic information, health habits, chronic medical problems, symptoms, quality of life, and the degree to which patients were bothered by night sweats, daytime sweating, and hot flashes.

RESULTS Among the 795 patients, 10% reported being bothered by night sweats, 9% by day sweats, and 8% by hot flashes. Eighteen percent reported at least 1 of these symptoms. The 3 symptoms were strongly correlated. Factors associated with night sweats in the multivariate models were age (odds ratio [OR] 0.94/y; 95% confidence interval [CI], 0.89–0.98), fever (OR 12.60; 95% CI, 6.58–24.14), muscle cramps (OR 2.84; 95% CI, 1.53–5.24), numbness of hands and feet (OR 3.34; 95% CI, 1.92–5.81), impaired vision (OR 2.45; 95% CI, 1.41–4.27), and hearing loss (OR 1.84; 95% CI, 1.03–3.27). Day sweats were associated with fever (OR 4.10; 95% CI, 2.14–7.87), restless legs (OR 3.22; 95% CI, 1.76–5.89), lightheadedness (OR 2.24; 95% CI, 1.30–3.88), and diabetes (OR 2.19; 95% CI, 1.22–3.92). Hot flashes were associated with nonwhite race (OR 3.10; 95% CI, 1.60–5.98), fever (OR 3.98; 95% CI, 1.97–8.04), bone pain (OR 2.31; CI 95%: 1.30–4.08), impaired vision (OR 2.12; 95% CI, 1.19–3.79), and nervous spells (OR 1.87; 95% CI, 1.01–3.46). All 3 symptoms were associated with reduced quality of life.

CONCLUSION Many older patients are bothered by night sweats, day sweats, and hot flashes. Though these symptoms are similar and related, they have somewhat different associations with other variables. Clinical evaluation should include questions about febrile illnesses, sensory deficits, anxiety, depression, pain, muscle cramps, and restless legs syndrome.