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Research Process Components Challenges Opportunities NIH = National Institutes of Health; AHRQ = Agency for Healthcare Quality and Research; PBRN = practice-based research network; IRB = Institutional Review Board; HIPPA = Health Insurance Portability and Accountability Act; EHR = electronic health record. Identifying knowledge gaps Understanding what is already known and identifying gaps in important knowledge from a generalist perspective and relevant to the health of people, families, communities, and health care in a family medicine setting Making known the tremendous complementarities between the NIH roadmap and the family medicine research approach Hypothesis generation Posing and focusing the right questions Engaging clinicians and communities in networks and participatory approaches Acquiring funding Lack of funding for primary care, noncategorical, research;study sections unfamiliar with practice-based, community participatory and integrative research Billionizing AHRQ; advocating for participation in review and leadership roles; promoting PBRNs;supporting Grant Generating Project Creating and maintaining research laboratories Supply of family medicine investigators with research skills and committed time; creation of family medicine patient cohorts Developing PBRN capacity; research centers for primary care health Executing studies Competing clinical demands with inadequate infrastructure and funding; research coordination across dispersed sites; IRB challenges; HIPAA Lobbying for funding; helping AHRQ advocate for central PBRN IRB and HIPAA authorization Analyzing data Sophistication of family medicine investigators in data analysis and qualitative research methods Research centers for primary care health; practice-and community-based research, and dissemination networks Dissemination Scarcity of scientific meetings for primary care research;underdeveloped mechanisms for engaging patients,communities, clinicians, and policymakers in knowledge generation and use Practice- and community-based research and dissemination networks; advancing support of Annals; support of mentoring projects Implementation Doing research in the setting (and from the perspective) in which findings will be applied to reduce the problem of translation into practice PBRNs; EHRs Identifying knowledge gaps The cycle starts again. (There are other iterative loops within the cycle). Work toward a culture of inquiry throughout family medicine