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Domain Specific Challenges Patient care Influence of behavioral, psychological, and social factors on illnesses Medically unexplained illnesses POEM (patient-oriented evidence that matters) Increasing need for patient participation Increasing complexity of interventions Patient-centered outcomes Health services delivery Rising demand with limited resources Accountability of services Alternative methods and models of care Integration of different services Professional development Variation in practice Adherence to management guidelines Practice of evidence-based medicine Critical appraisal Information overload
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