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Research ArticleOriginal Research

Concerns Regarding Gynecological Aspects of Brazilian Girls and Women With Down Syndrome: A Cross-Sectional Study of Caregivers’ Opinions

Gustavo Wandresen, Fernanda Sgarbi, Lais Tomiura, Nancy Palmieri de Oliveira and Renato Nisihara
The Annals of Family Medicine July 2023, 21 (4) 322-326; DOI: https://doi.org/10.1370/afm.2993
Gustavo Wandresen
1Post Graduate Program in Gynecology and Obstetrics, Federal University of Paraná, Curitiba, Brazil
MD
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Fernanda Sgarbi
2University Positivo, Curitiba, Brazil
MD
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Lais Tomiura
3Mackenzie Evangelical School of Medicine Paraná, Curitiba, Brazil
MD
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Nancy Palmieri de Oliveira
4Federal University of Paraná, Curitiba, Brazil
MD
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Renato Nisihara
1Post Graduate Program in Gynecology and Obstetrics, Federal University of Paraná, Curitiba, Brazil
2University Positivo, Curitiba, Brazil
3Mackenzie Evangelical School of Medicine Paraná, Curitiba, Brazil
PhD
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  • For correspondence: renatonisihara@gmail.com
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    Figure 1.

    Caregiver concerns about menstrual cycles.

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    Table 1.

    Questions About Gynecological Care of Patients With Down Syndrome

    How long does the caregiver stay with the patient?
    What is your main concern or difficulty regarding puberty?
    Have there been secondary sexual characteristics? (breasts, hair, vaginal bleeding) If yes, at what age?
    How often does menstruation occur?
    Do you notice pain with menstruation? Changes in behavior?
    Does the patient use any medication to delay the onset of menstruation?
    Would you like some medication to be used to delay the onset of menstruation?
    Does the patient use any medication to control menstrual symptoms?
    Do you think it is necessary to use any method or medication to control bleeding/menstruation?
    What type of treatment to prevent pregnancy and/or reduce/abolish menstrual bleeding would you like the patient to use?
    Does the patient use any method of contraception? If so which type? Did you notice side effects? Have you had to stop using it? What reason?
    Does the occurrence of menstruation make it impossible or has already made it impossible for the patient to attend school, work, or other social activities?
    Would you allow/not allow a loving relationship (dating, without sex)?
    Would you allow/not allow intimate relationships, consensual sexual relations?
    Do you think there is a need for guidance on STDs (sexually transmitted diseases)?
    Do you agree to perform a surgical method to sterilize the patient?
    Has the patient ever consulted with a doctor or gynecologist?
    Has the patient ever had sexual intercourse in her life?
    Has the patient ever had treatment for vaginal infection/discharge?
    Does the patient perform personal hygiene alone?
    • View popup
    Table 2.

    Characteristics of Patients (N = 100)

    Characteristic (No.)Mean (SD)Range
    Age (n = 100), y17.4 (8.4)9-47
    Weight (n = 98), kg50.5 (14.8)28-88
    Height (n = 95), m  1.42 (0.1)1.1-1.6
    Thelarche (n = 77), y11.1 (1.7)8-15
    Pubarche (n = 82), y10.9 (1.6)7-15
    Menarche (n = 78), y11.8 (1.5)9-15
    • View popup
    Table 3.

    Characteristics Related to Menstruation (N = 78)

    Symptoms related to menstruation, %
    Behavior changes74.0
    Pain62.3
    Pain and behavior changes44.1
    Did not answer  6.0
    Frequency of menstruation, %
    Monthly88.3
    Unpredictable  9.1
    Twice a month  2.6
    Medications to control menstrual symptoms, %
    Antispasmodics13.0
    NSAIDs11.0
    Hormones  7.0
    Analgesics  4.0
    Others  3.0
    • NSAID = nonsteroidal anti-inflammatory drug.

    • View popup
    Table 4.

    Contraception Methods and Side Effects (N = 14)

    Contraception MethodNo. (%)Side EffectsNo.
    Oral pills
      With interval7 (50.0)Weight gain4
      Without interval2 (14.4)Skin changesa1
    Quarterly injectable (MPA)3 (21.4)Weight gain1
    Monthly injectable (MPA)1 (7.2)Did not answer1
    Intrauterine device1 (7.2)Weight gain1
    • MPA = medroxyprogesterone acetate.

    • ↵a Oily, acne, spots on the skin.

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The Annals of Family Medicine: 21 (4)
The Annals of Family Medicine: 21 (4)
Vol. 21, Issue 4
July/August 2023
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Concerns Regarding Gynecological Aspects of Brazilian Girls and Women With Down Syndrome: A Cross-Sectional Study of Caregivers’ Opinions
Gustavo Wandresen, Fernanda Sgarbi, Lais Tomiura, Nancy Palmieri de Oliveira, Renato Nisihara
The Annals of Family Medicine Jul 2023, 21 (4) 322-326; DOI: 10.1370/afm.2993

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Concerns Regarding Gynecological Aspects of Brazilian Girls and Women With Down Syndrome: A Cross-Sectional Study of Caregivers’ Opinions
Gustavo Wandresen, Fernanda Sgarbi, Lais Tomiura, Nancy Palmieri de Oliveira, Renato Nisihara
The Annals of Family Medicine Jul 2023, 21 (4) 322-326; DOI: 10.1370/afm.2993
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