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OtherReflections

The Break-Even Point: When Medical Advances Are Less Important Than Improving the Fidelity With Which They Are Delivered

Steven H. Woolf and Robert E. Johnson
The Annals of Family Medicine November 2005, 3 (6) 545-552; DOI: https://doi.org/10.1370/afm.406
Steven H. Woolf
MD, MPH
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Robert E. Johnson
PhD
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Abstract

Society invests billions of dollars in the development of new drugs and technologies but comparatively little in the fidelity of health care, that is, improving systems to ensure the delivery of care to all patients in need. Using mathematical arguments and a nomogram, we demonstrate that technological advances must yield dramatic, often unrealistic increases in efficacy to do more good than could be accomplished by improving fidelity. In 2 examples (the development of anti-platelet agents and statins), we show that enhanced efficacy failed to achieve the health gains that would have occurred by delivering older agents to all eligible patients. Society’s huge investment in technological innovations that only modestly improve efficacy, by consuming resources needed for improved delivery of care, may cost more lives than it saves. The misalignment of priorities is driven partly by the commercial interests of industry and by the public’s appetite for technological breakthroughs, but health outcomes ultimately suffer. Health, economic, and moral arguments make the case for spending less on technological advances and more on improving systems for delivering care.

  • Allocation of resources
  • delivery of health care
  • priority setting
  • disparities
  • quality of health care

Footnotes

  • Conflicts of interest: none reported

  • Presented in part at the AcademyHealth 2004 Annual Meeting, San Diego, Calif, June 8, 2004.

  • Received for publication January 3, 2005.
  • Revision received May 25, 2005.
  • Accepted for publication May 31, 2005.
  • © 2005 Annals of Family Medicine, Inc.
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The Annals of Family Medicine: 3 (6)
The Annals of Family Medicine: 3 (6)
Vol. 3, Issue 6
1 Nov 2005
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The Break-Even Point: When Medical Advances Are Less Important Than Improving the Fidelity With Which They Are Delivered
Steven H. Woolf, Robert E. Johnson
The Annals of Family Medicine Nov 2005, 3 (6) 545-552; DOI: 10.1370/afm.406

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The Break-Even Point: When Medical Advances Are Less Important Than Improving the Fidelity With Which They Are Delivered
Steven H. Woolf, Robert E. Johnson
The Annals of Family Medicine Nov 2005, 3 (6) 545-552; DOI: 10.1370/afm.406
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  • Article
    • Abstract
    • INTRODUCTION
    • SOCIETY’S PRIORITIES
    • HEALTH GAINS OF EFFICACY AND FIDELITY IN PERSPECTIVE
    • IS THE COMPARISON FAIR?
    • LIMITATIONS
    • COMPETING AGENDAS
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