Prescribing Cascades Among Older Community-Dwelling Adults: Application of Prescription Sequence Symmetry Analysis to a National Database in Ireland

Ann Sinéad Doherty; Lars Christian Lund; Frank Moriarty; Fiona Boland; Barbara Clyne; Tom Fahey; Seán P. Kennelly; Denis O’Mahony; Emma Wallace

doi:10.1370/afm.240383

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Prescribing Cascades Among Older Community-Dwelling Adults: Application of Prescription Sequence Symmetry Analysis to a National Database in Ireland

Ann Sinéad Doherty, Lars Christian Lund, Frank Moriarty, Fiona Boland, Barbara Clyne, Tom Fahey, Seán P. Kennelly, Denis O’Mahony and Emma Wallace

The Annals of Family Medicine June 2025, 240383; DOI: https://doi.org/10.1370/afm.240383

Ann Sinéad Doherty

Department of General Practice, School of Medicine, University College Cork, Cork, Ireland

PhD

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Lars Christian Lund

Clinical Pharmacology, Pharmacy and Environmental Medicine, Department of Public Health, University of Southern Denmark, Odense, Denmark

PhD

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Frank Moriarty

School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland (RCSI) University of Medicine and Health Sciences, Dublin, Ireland

PhD

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Fiona Boland

Data Science Centre, Royal College of Surgeons in Ireland (RCSI) University of Medicine and Health Sciences, Dublin, Ireland

PhD

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Barbara Clyne

Department of Public Health and Epidemiology, School of Population Health, Royal College of Surgeons (RCSI) University of Medicine and Health Sciences, Dublin, Ireland

PhD

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Tom Fahey

Department of General Practice, Royal College of Surgeons in Ireland (RCSI) University of Medicine and Health Sciences, Dublin, Ireland

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Seán P. Kennelly

Department of Age-related Healthcare, Tallaght University Hospital, Dublin, Ireland

Department of Medical Gerontology, School of Medicine, Trinity College Dublin, Dublin, Ireland

PhD

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Denis O’Mahony

Department of Medicine (Geriatrics), School of Medicine, University College Cork, Cork, Ireland

Geriatric Medicine, Cork University Hospital, Cork, Ireland

DSc

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Emma Wallace

Department of General Practice, School of Medicine, University College Cork, Cork, Ireland

PhD

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The Annals of Family Medicine: 23 (3)

Vol. 23, Issue 3

May/June 2025

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Prescribing Cascades Among Older Community-Dwelling Adults: Application of Prescription Sequence Symmetry Analysis to a National Database in Ireland

Ann Sinéad Doherty, Lars Christian Lund, Frank Moriarty, Fiona Boland, Barbara Clyne, Tom Fahey, Seán P. Kennelly, Denis O’Mahony, Emma Wallace

The Annals of Family Medicine Jun 2025, 240383; DOI: 10.1370/afm.240383

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Prescribing Cascades Among Older Community-Dwelling Adults: Application of Prescription Sequence Symmetry Analysis to a National Database in Ireland

Ann Sinéad Doherty, Lars Christian Lund, Frank Moriarty, Fiona Boland, Barbara Clyne, Tom Fahey, Seán P. Kennelly, Denis O’Mahony, Emma Wallace

The Annals of Family Medicine Jun 2025, 240383; DOI: 10.1370/afm.240383

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Keywords

prescribing cascades
drug-related side effects and adverse reactions
pharmacoepidemiology
aged
geriatrics
medication-related harm
polypharmacy
prescription drugs
inappropriate prescribing
physician prescribing patterns

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