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Research ArticleOriginal Research

Prescription Opioid Duration, Dose, and Increased Risk of Depression in 3 Large Patient Populations

Jeffrey F. Scherrer, Joanne Salas, Laurel A. Copeland, Eileen M. Stock, Brian K. Ahmedani, Mark D. Sullivan, Thomas Burroughs, F. David Schneider, Kathleen K. Bucholz and Patrick J. Lustman
The Annals of Family Medicine January 2016, 14 (1) 54-62; DOI: https://doi.org/10.1370/afm.1885
Jeffrey F. Scherrer
1Department of Family and Community Medicine, Saint Louis University School of Medicine, St. Louis, Missouri
2Harry S. Truman Veterans Administration Medical Center, Columbia, Missouri
3Saint Louis University Center for Outcomes Research, St. Louis, Missouri
PhD
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  • For correspondence: scherrjf@slu.edu
Joanne Salas
1Department of Family and Community Medicine, Saint Louis University School of Medicine, St. Louis, Missouri
2Harry S. Truman Veterans Administration Medical Center, Columbia, Missouri
MPH
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Laurel A. Copeland
4Center for Applied Health Research, Baylor Scott & White Health, and Central Texas Veterans Health Care System, Temple, Texas
5Texas A&M Health Science Center, Bryan, Texas
6University of Texas Health Science Center, San Antonio, Texas
PhD
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Eileen M. Stock
4Center for Applied Health Research, Baylor Scott & White Health, and Central Texas Veterans Health Care System, Temple, Texas
5Texas A&M Health Science Center, Bryan, Texas
PhD
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Brian K. Ahmedani
7Henry Ford Health System, Center for Health Policy and Health Services Research, Detroit, Michigan
PhD
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Mark D. Sullivan
8Department of Psychiatry and Behavioral Health, University of Washington School of Medicine, Seattle, Washington
MD
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Thomas Burroughs
3Saint Louis University Center for Outcomes Research, St. Louis, Missouri
PhD
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F. David Schneider
1Department of Family and Community Medicine, Saint Louis University School of Medicine, St. Louis, Missouri
MD, MSPH
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Kathleen K. Bucholz
9Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri
PhD
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Patrick J. Lustman
9Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri
10The Bell Street Clinic, VA St. Louis Health Care System – John Cochran Division, St. Louis, Missouri
PhD
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Article Information

vol. 14 no. 1 54-62
DOI 
https://doi.org/10.1370/afm.1885
PubMed 
26755784

Published By 
The Annals of Family Medicine
Print ISSN 
1544-1709
Online ISSN 
1544-1717
History 
  • Received for publication June 29, 2015
  • Revision received September 17, 2015
  • Accepted for publication October 19, 2015
  • Published online January 11, 2016.

Copyright & Usage 
© 2016 Annals of Family Medicine, Inc.

Author Information

  1. Jeffrey F. Scherrer, PhD1,2,3⇑,
  2. Joanne Salas, MPH1,2,
  3. Laurel A. Copeland, PhD4,5,6,
  4. Eileen M. Stock, PhD4,5,
  5. Brian K. Ahmedani, PhD7,
  6. Mark D. Sullivan, MD8,
  7. Thomas Burroughs, PhD3,
  8. F. David Schneider, MD, MSPH1,
  9. Kathleen K. Bucholz, PhD9 and
  10. Patrick J. Lustman, PhD9,10
  1. 1Department of Family and Community Medicine, Saint Louis University School of Medicine, St. Louis, Missouri
  2. 2Harry S. Truman Veterans Administration Medical Center, Columbia, Missouri
  3. 3Saint Louis University Center for Outcomes Research, St. Louis, Missouri
  4. 4Center for Applied Health Research, Baylor Scott & White Health, and Central Texas Veterans Health Care System, Temple, Texas
  5. 5Texas A&M Health Science Center, Bryan, Texas
  6. 6University of Texas Health Science Center, San Antonio, Texas
  7. 7Henry Ford Health System, Center for Health Policy and Health Services Research, Detroit, Michigan
  8. 8Department of Psychiatry and Behavioral Health, University of Washington School of Medicine, Seattle, Washington
  9. 9Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri
  10. 10The Bell Street Clinic, VA St. Louis Health Care System – John Cochran Division, St. Louis, Missouri
  1. CORRESPONDING AUTHOR: Jeffrey F. Scherrer, PhD, Family and Community Medicine, Saint Louis University School of Medicine, 1402 N Grand Blvd, St. Louis, MO 63104, scherrjf{at}slu.edu

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The Annals of Family Medicine: 14 (1)
The Annals of Family Medicine: 14 (1)
Vol. 14, Issue 1
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Prescription Opioid Duration, Dose, and Increased Risk of Depression in 3 Large Patient Populations
Jeffrey F. Scherrer, Joanne Salas, Laurel A. Copeland, Eileen M. Stock, Brian K. Ahmedani, Mark D. Sullivan, Thomas Burroughs, F. David Schneider, Kathleen K. Bucholz, Patrick J. Lustman
The Annals of Family Medicine Jan 2016, 14 (1) 54-62; DOI: 10.1370/afm.1885

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Prescription Opioid Duration, Dose, and Increased Risk of Depression in 3 Large Patient Populations
Jeffrey F. Scherrer, Joanne Salas, Laurel A. Copeland, Eileen M. Stock, Brian K. Ahmedani, Mark D. Sullivan, Thomas Burroughs, F. David Schneider, Kathleen K. Bucholz, Patrick J. Lustman
The Annals of Family Medicine Jan 2016, 14 (1) 54-62; DOI: 10.1370/afm.1885
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Subjects

  • Domains of illness & health:
    • Mental health
    • Disease pathophysiology / etiology
  • Person groups:
    • Vulnerable populations
  • Methods:
    • Quantitative methods
  • Other topics:
    • Disparities in health and health care

Keywords

  • analgesics, opioid
  • depression
  • cohort
  • epidemiology

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