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Research ArticleOriginal Research

Diagnostic Accuracy of Fecal Calprotectin for Pediatric Inflammatory Bowel Disease in Primary Care: A Prospective Cohort Study

Gea A. Holtman, Yvonne Lisman-van Leeuwen, Boudewijn J. Kollen, Obbe F. Norbruis, Johanna C. Escher, Angelika Kindermann, Yolanda B. de Rijke, Patrick F. van Rheenen and Marjolein Y. Berger
The Annals of Family Medicine September 2016, 14 (5) 437-445; DOI: https://doi.org/10.1370/afm.1949
Gea A. Holtman
1Department of General Practice, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
MSc
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Yvonne Lisman-van Leeuwen
1Department of General Practice, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
PhD
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Boudewijn J. Kollen
1Department of General Practice, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
PhD
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Obbe F. Norbruis
2Department of Pediatrics, Isala Hospital, Zwolle, The Netherlands
MD, PhD
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Johanna C. Escher
3Department of Pediatric Gastroenterology, Erasmus University Medical Centre-Sophia Children’s Hospital, Rotterdam, The Netherlands
MD, PhD
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Angelika Kindermann
4Department of Pediatric Gastroenterology, Emma Children’s Hospital ⁄ Academic Medical Center, Amsterdam, The Netherlands
MD, PhD
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Yolanda B. de Rijke
5Department of Clinical Chemistry, Erasmus University Medical Centre, Rotterdam, The Netherlands
MD, PhD
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Patrick F. van Rheenen
6Department of Pediatric Gastroenterology, Beatrix Children’s Hospital ⁄ University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
MD, PhD
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Marjolein Y. Berger
1Department of General Practice, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
MD, PhD
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  • For correspondence: m.y.berger@umcg.nl
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Article Information

vol. 14 no. 5 437-445
DOI 
https://doi.org/10.1370/afm.1949
PubMed 
27621160

Published By 
The Annals of Family Medicine
Print ISSN 
1544-1709
Online ISSN 
1544-1717
History 
  • Received for publication October 5, 2015
  • Revision received March 7, 2016
  • Accepted for publication March 16, 2016
  • Published online September 12, 2016.

Copyright & Usage 
© 2016 Annals of Family Medicine, Inc.

Author Information

  1. Gea A. Holtman, MSc1,
  2. Yvonne Lisman-van Leeuwen, PhD1,
  3. Boudewijn J. Kollen, PhD1,
  4. Obbe F. Norbruis, MD, PhD2,
  5. Johanna C. Escher, MD, PhD3,
  6. Angelika Kindermann, MD, PhD4,
  7. Yolanda B. de Rijke, MD, PhD5,
  8. Patrick F. van Rheenen, MD, PhD6 and
  9. Marjolein Y. Berger, MD, PhD1⇑
  1. 1Department of General Practice, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
  2. 2Department of Pediatrics, Isala Hospital, Zwolle, The Netherlands
  3. 3Department of Pediatric Gastroenterology, Erasmus University Medical Centre-Sophia Children’s Hospital, Rotterdam, The Netherlands
  4. 4Department of Pediatric Gastroenterology, Emma Children’s Hospital ⁄ Academic Medical Center, Amsterdam, The Netherlands
  5. 5Department of Clinical Chemistry, Erasmus University Medical Centre, Rotterdam, The Netherlands
  6. 6Department of Pediatric Gastroenterology, Beatrix Children’s Hospital ⁄ University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
  1. CORRESPONDING AUTHOR: Marjolein Y. Berger, MD, PhD, Department of General Practice, FA21, University Medical Center Groningen, University of Groningen, PO Box 196, 9700 AD, Groningen, The Netherlands, m.y.berger{at}umcg.nl

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The Annals of Family Medicine: 14 (5)
The Annals of Family Medicine: 14 (5)
Vol. 14, Issue 5
September/October 2016
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Diagnostic Accuracy of Fecal Calprotectin for Pediatric Inflammatory Bowel Disease in Primary Care: A Prospective Cohort Study
Gea A. Holtman, Yvonne Lisman-van Leeuwen, Boudewijn J. Kollen, Obbe F. Norbruis, Johanna C. Escher, Angelika Kindermann, Yolanda B. de Rijke, Patrick F. van Rheenen, Marjolein Y. Berger
The Annals of Family Medicine Sep 2016, 14 (5) 437-445; DOI: 10.1370/afm.1949

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Diagnostic Accuracy of Fecal Calprotectin for Pediatric Inflammatory Bowel Disease in Primary Care: A Prospective Cohort Study
Gea A. Holtman, Yvonne Lisman-van Leeuwen, Boudewijn J. Kollen, Obbe F. Norbruis, Johanna C. Escher, Angelika Kindermann, Yolanda B. de Rijke, Patrick F. van Rheenen, Marjolein Y. Berger
The Annals of Family Medicine Sep 2016, 14 (5) 437-445; DOI: 10.1370/afm.1949
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Cited By...

  • Effect of faecal calprotectin testing on referrals for children with chronic gastrointestinal symptoms in primary care: study protocol for a cluster randomised controlled trial
  • Point-of-care faecal calprotectin testing in patients with paediatric inflammatory bowel disease during the COVID-19 pandemic
  • Predicting inflammatory bowel disease in children with abdominal pain and diarrhoea: calgranulin-C versus calprotectin stool tests
  • In This Issue: Different Paths to Discovery
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More in this TOC Section

  • Teamwork Among Primary Care Staff to Achieve Regular Follow-Up of Chronic Patients
  • Shared Decision Making Among Racially and/or Ethnically Diverse Populations in Primary Care: A Scoping Review of Barriers and Facilitators
  • Convenience or Continuity: When Are Patients Willing to Wait to See Their Own Doctor?
Show more Original Research

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Subjects

  • Domains of illness & health:
    • Chronic illness
  • Person groups:
    • Children's health
  • Methods:
    • Quantitative methods
  • Other research types:
    • POEMs
    • Professional practice

Keywords

  • inflammatory bowel disease
  • calprotectin
  • child
  • sensitivity and specificity
  • primary health care
  • practice-based research

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