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Research ArticleMethodology

Comparative Associations Between Measures of Anti-cholinergic Burden and Adverse Clinical Outcomes

Wen-Han Hsu, Yu-Wen Wen, Liang-Kung Chen and Fei-Yuan Hsiao
The Annals of Family Medicine November 2017, 15 (6) 561-569; DOI: https://doi.org/10.1370/afm.2131
Wen-Han Hsu
1Graduate Institute of Clinical Pharmacy, College of Medicine, National Taiwan University, Taipei, Taiwan
MS
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Yu-Wen Wen
2Clinical Informatics and Medical Statistics Research Center, Chang Gung University, Taoyuan City, Taiwan
PhD
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Liang-Kung Chen
3Aging and Health Research Center, National Yang-Ming University, Taipei, Taiwan
4Center for Geriatrics and Gerontology, Taipei Veterans General Hospital, Taipei, Taiwan
5Institute of Public Health, School of Medicine, National Yang-Ming University, Taipei, Taiwan
MD, PhD
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Fei-Yuan Hsiao
1Graduate Institute of Clinical Pharmacy, College of Medicine, National Taiwan University, Taipei, Taiwan
6School of Pharmacy, College of Medicine, National Taiwan University, Taipei, Taiwan
7Department of Pharmacy, National Taiwan University Hospital, Taipei, Taiwan
PhD
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  • For correspondence: fyshsiao@ntu.edu.tw
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Article Information

vol. 15 no. 6 561-569
DOI 
https://doi.org/10.1370/afm.2131
PubMed 
29133497

Published By 
The Annals of Family Medicine
Print ISSN 
1544-1709
Online ISSN 
1544-1717
History 
  • Received for publication October 17, 2016
  • Revision received May 16, 2017
  • Accepted for publication June 22, 2017
  • Published online November 13, 2017.

Copyright & Usage 
© 2017 Annals of Family Medicine, Inc.

Author Information

  1. Wen-Han Hsu, MS1,
  2. Yu-Wen Wen, PhD2,
  3. Liang-Kung Chen, MD, PhD3,4,5 and
  4. Fei-Yuan Hsiao, PhD1,6,7⇑
  1. 1Graduate Institute of Clinical Pharmacy, College of Medicine, National Taiwan University, Taipei, Taiwan
  2. 2Clinical Informatics and Medical Statistics Research Center, Chang Gung University, Taoyuan City, Taiwan
  3. 3Aging and Health Research Center, National Yang-Ming University, Taipei, Taiwan
  4. 4Center for Geriatrics and Gerontology, Taipei Veterans General Hospital, Taipei, Taiwan
  5. 5Institute of Public Health, School of Medicine, National Yang-Ming University, Taipei, Taiwan
  6. 6School of Pharmacy, College of Medicine, National Taiwan University, Taipei, Taiwan
  7. 7Department of Pharmacy, National Taiwan University Hospital, Taipei, Taiwan
  1. CORRESPONDING AUTHOR: Fei-Yuan Hsiao, PhD, Graduate Institute of Clinical Pharmacy, Room 220, 33, Linsen S Rd, College of Medicine, National Taiwan University, Taipei, Taiwan 10050, fyshsiao{at}ntu.edu.tw
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Comparative Associations Between Measures of Anti-cholinergic Burden and Adverse Clinical Outcomes
Wen-Han Hsu, Yu-Wen Wen, Liang-Kung Chen, Fei-Yuan Hsiao
The Annals of Family Medicine Nov 2017, 15 (6) 561-569; DOI: 10.1370/afm.2131

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Comparative Associations Between Measures of Anti-cholinergic Burden and Adverse Clinical Outcomes
Wen-Han Hsu, Yu-Wen Wen, Liang-Kung Chen, Fei-Yuan Hsiao
The Annals of Family Medicine Nov 2017, 15 (6) 561-569; DOI: 10.1370/afm.2131
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Subjects

  • Domains of illness & health:
    • Chronic illness
    • Disease pathophysiology / etiology
  • Person groups:
    • Older adults
  • Methods:
    • Quantitative methods
  • Other research types:
    • Health services
  • Other topics:
    • Research capacity building

Keywords

  • anticholinergic burden
  • Anticholinergic Risk Scale (ARS)
  • Anticholinergic Cognitive Burden scale (ACB)
  • Drug Burden Index - Anticholinergic component (DBI-Ach)
  • emergency department visits
  • hospitalizations
  • fractures
  • dementia
  • adverse effects
  • older adults
  • aged
  • primary care

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